GPL14943[Accession] - GEO DataSets

(Submitter supplied) Blood exsosomal miRNAs of patients with normal livers, to be compared with liver diseas patients Aiming to develop circulatin biomarkers for liver disease, including progresson of fibrosis/inflammation. This data set should be uasd as control samples to be compared with liver disease patients.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
76 Samples

Download data: TXT

Series

Accession:: GSE82301

ID:: 200082301

Analyze with GEO2R

Select item 2000910264.

Global miRNA expression profiles of fibroblast-like synoviocytes in patients with rheumatoid arthritis and osteoarthritis

(Submitter supplied) Fibroblast-like synoviocyte (FLS) constitutes a major cell subset of rheumatoid arthritis (RA) joint. Dysregulation of microRNAs (miRNAs) contributes to FLS activation in the context of chronic inflammation. However, functional association of the miRNAs-targets relationships characterizing FLS phenotypes in RA has not been fully elucidated yet. Thus, we uncovered the novel miRNA-target interactions characterizing pathologic phenotypes of RA-FLS. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
8 Samples

Download data: TXT

Series

Accession:: GSE91026

ID:: 200091026

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000868895.

A genome-wide microRNA profiling indicates miR-424-5p and miR-503-5p as regulators of ALK expression in neuroblastoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
35 Samples

Download data: TXT

Series

Accession:: GSE86889

ID:: 200086889

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000866526.

A genome-wide microRNA profiling indicates miR-424-5p and miR-503-5p as regulators of ALK expression in neuroblastoma(NB Samples)

(Submitter supplied) The discovery of either missense mutations or amplification of ALK (Anaplastic Lymphoma Kinase) gene identified this receptor tyrosine kinase as a therapeutic target in neuroblastoma (NB). Moreover, a high ALK expression has been associated with cases of metastatic NB and with a worse prognosis. In order to identify miRNAs involved in the regulation of ALK expression in NB we therefore analyzed their expression profile in 16 NB cell lines and in 22 patients by qPCR. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
20 Samples

Download data: TXT

Series

Accession:: GSE86652

ID:: 200086652

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000848417.

A genome-wide microRNA profiling indicates miR-424-5p and miR-503-5p as regulators of ALK expression in neuroblastoma (NB cell lines)

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
15 Samples

Download data: TXT

Series

Accession:: GSE84841

ID:: 200084841

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000381678.

Decreased expression of key tumour suppressor microRNAs is associated with lymph node metastases in triple negative breast cancer

(Submitter supplied) Breast cancer is the most common malignancy that develops in women, responsible for the highest cancer-associated death rates. Triple negative breast cancers (TNBC) represent an important subtype that have an aggressive clinical phenotype, are associated with a higher likelihood of metastasis and are not responsive to current targeted therapies. miRNAs have emerged as an attractive candidate for molecular biomarkers and treatment targets in breast cancer, but their role in the progression of TNBC remains largely unexplored. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
67 Samples

Download data: TXT

Series

Accession:: GSE38167

ID:: 200038167

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000635419.

Adventitial tertiary lymphoid organs in AAA are a potential source of miRNAs as biomarkers

(Submitter supplied) This study aims to identify and characterize miRNA expression inATLOs isolated by laser microdissection from human AAA biopsy samples. The aim of this study was to profile (with microarray technology) miRNAs in ATLOs (Adventitial tertiary lymphoid organs), isolated by laser capture microdissection (LCM). Smooth muscle cells (SMCs) isolated from control non-aneurysmal aortas were the control group according to which data were normalized. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platforms:: GPL14767 GPL14943
4 Samples

Download data: TXT

Series

Accession:: GSE63541

ID:: 200063541

PubMed Full text in PMC Similar studies

Select item 20006217910.

MicroRNA profiling of cells isolated from human abdominal aortic aneurysms. Let-7f, a new potential circulating biomarker

(Submitter supplied) This study aims to identify and characterize miRNA expression in aneurysmal smooth muscle cells (SMCs) and M1 and M2 macrophages isolated by laser microdissection from human AAA biopsy samples. The aim of this study was to profile (with microarray technology) miRNAs in M1 and M2 macrophages and Smooth muscle cells (SMCs), isolated by laser capture microdissection (LCM). SMCs isolated from control non-aneurysmal aortas were the control group according to which data were normalized. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platforms:: GPL14767 GPL14943
10 Samples

Download data: TXT

Series

Accession:: GSE62179

ID:: 200062179

PubMed Full text in PMC Similar studies

Select item 20004848511.

Global microRNA expression profiling of serum from healthy controls vs serum from ovarian cancer patients

(Submitter supplied) Global microRNA expression profiling of serum were collected using Agilent miRNA microarrays (G4471A Human, Amadid 29297, Sanger 14) carrying 887 individual human miRNA probes. Two different sources of RNA were analyzed: serum from healthy controls (N=5) and patients with ovarian carcinoma (CA, n=5)

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
10 Samples

Download data: TXT

Series

Accession:: GSE48485

ID:: 200048485

Select item 20004637612.

Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL13497 GPL14943
8 Samples

Download data: TXT

Series

Accession:: GSE46376

ID:: 200046376

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004637513.

Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21 [miRNA expression]

(Submitter supplied) The epidemiologic association between statin use and decreased risk of advanced prostate cancer suggests that statins may inhibit prostate cancer development and/or progression. Studies were performed to determine the effects of a model statin, atorvastatin (ATO), on the proliferation and differentiation of prostate cancer cells, and to identify possible mechanisms of ATO action. ATO inhibited the in vitro proliferation of both LNCaP and PC3 human prostate cancer cells in dose-dependent fashion. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
4 Samples

Download data: TXT

Series

Accession:: GSE46375

ID:: 200046375

PubMed Full text in PMC Similar studies

Select item 20003405214.

Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma

(Submitter supplied) Global microRNA expression profiling of serum were collected using Agilent miRNA microarrays (G4471A Human, Amadid 29297, Sanger 14) carrying 887 individual human miRNA probes. Two different sources of RNA were analyzed: serum from NMRI-nu/nu mice carrying a xenograft tumor derived from human primary pancreatic ductal adenocarcinomas (CA, n=6) and serum from tumor free control NMRI-nu/nu mice (N, n=6)

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
12 Samples

Download data: TXT

Series

Accession:: GSE34052

ID:: 200034052

Select item 20004082015.

Differences in miRNA Detection Levels are Technology and Sequence Dependent

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL11154 GPL14613 GPL14943
45 Samples

Download data: CEL, TXT

Series

Accession:: GSE40820

ID:: 200040820

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004081516.

Differences in miRNA Detection Levels are Technology and Sequence Dependent [Agilent array]

(Submitter supplied) We undertook an integrative technological approach to compare miRNA detection capability of three high-throughput commercial platforms.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14943
17 Samples

Download data: TXT

Series

Accession:: GSE40815

ID:: 200040815

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004111717.

Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array; Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL5175 GPL13534 GPL14943
132 Samples

Download data: CEL, TXT

Series

Accession:: GSE41117

ID:: 200041117

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004111518.

Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers (microRNA)

(Submitter supplied) Oral cavity squamous cell carcinoma (OSCC) is a disease with extensive morbidity and mortality and few useful molecular targets. Multiplatform integrated genomic analysis was performed in order to identify genomic drivers and molecularly discernible tumor subtypes. mRNA, miRNA and methylation data are all submitted to GEO