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Items: 13

1.

Mesoscale chromatin confinement facilitates target search of pioneer transcription factors in live cells [RNA-seq]

(Submitter supplied) To dissect the molecular mechanisms of the transcription factor FOXA2 accessing nucleosomal targets and controlling cell fates, we combined live-cell single-molecule imaging, genome editing, chromatin binding, chromatin accessibility, and RNA sequence analysis. Using the hESC differentiation cellular system to anterior primitive streak (APS) and definitive endoderm (DE), we demonstrated by RNA-seq that FOXA2 is a lineage-determining transcription factor for DE formation and that its intrinsically disordered C-terminal domain (CTD) is essential for its normal function. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
11 Samples
Download data: BW, TXT
Series
Accession:
GSE203640
ID:
200203640
2.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
3.

dCdN10_DE

Organism:
Homo sapiens
Source name:
definitive endoderm
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181143
ID:
306181143
4.

dCdN10_APS

Organism:
Homo sapiens
Source name:
anterior primitive streak
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181142
ID:
306181142
5.

dC11_DE

Organism:
Homo sapiens
Source name:
definitive endoderm
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181141
ID:
306181141
6.

dC11_APS

Organism:
Homo sapiens
Source name:
anterior primitive streak
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181140
ID:
306181140
7.

KO21_DE

Organism:
Homo sapiens
Source name:
definitive endoderm
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181139
ID:
306181139
8.

KO21_APS

Organism:
Homo sapiens
Source name:
anterior primitive streak
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181138
ID:
306181138
9.

KO1_DE

Organism:
Homo sapiens
Source name:
definitive endoderm
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181137
ID:
306181137
10.

KO1_APS

Organism:
Homo sapiens
Source name:
anterior primitive streak
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181136
ID:
306181136
11.

WT_DE

Organism:
Homo sapiens
Source name:
definitive endoderm
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181135
ID:
306181135
12.

WT_APS

Organism:
Homo sapiens
Source name:
anterior primitive streak
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181134
ID:
306181134
13.

WT_ES

Organism:
Homo sapiens
Source name:
embryonic stem cells
Platform:
GPL20301
Series:
GSE203640 GSE203650
Download data: BW, TXT
Sample
Accession:
GSM6181133
ID:
306181133
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Supplemental Content

db=gds|term=GSE203640[Accession]|query=1|qty=2|blobid=MCID_66687136bb845b085b566c7e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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