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Items: 19

1.

Mesoscale chromatin confinement facilitates target search of pioneer transcription factors in live cells [ChIP-seq]

(Submitter supplied) To dissect the molecular mechanisms of the transcription factor FOXA2 accessing nucleosomal targets and controlling cell fates, we combined live-cell single-molecule imaging, genome editing, chromatin binding, chromatin accessibility, and RNA sequence analysis. Using the hESC differentiation cellular system to anterior primitive streak (APS) and definitive endoderm (DE), we demonstrated by RNA-seq that FOXA2 is a lineage-determining transcription factor for DE formation and that its intrinsically disordered C-terminal domain (CTD) is essential for its normal function. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
17 Samples
Download data: BED, BW, NARROWPEAK
Series
Accession:
GSE203644
ID:
200203644
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

U2OS_SOX2FLFOXA2CTD_day4_bio rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data
Sample
Accession:
GSM7996358
ID:
307996358
4.

U2OS_SOX2FLFOXA2CTD_day4_bio rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996357
ID:
307996357
5.

U2OS_SOX2FL_day4_bio rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data
Sample
Accession:
GSM7996356
ID:
307996356
6.

U2OS_SOX2FL_day4_bio rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996355
ID:
307996355
7.

U2OS_FOXA3dCTD_day4_biol rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BW
Sample
Accession:
GSM7996354
ID:
307996354
8.

U2OS_FOXA3dCTD_day4_biol rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996353
ID:
307996353
9.

U2OS_FOXA1dCTD_day4_biol rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BW
Sample
Accession:
GSM7996352
ID:
307996352
10.

U2OS_FOXA1dCTD_day4_biol rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996351
ID:
307996351
11.

U2OS_FOXA3FL_day4_biol rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BW
Sample
Accession:
GSM7996350
ID:
307996350
12.

U2OS_FOXA3FL_day4_biol rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996349
ID:
307996349
13.

U2OS_FOXA1FL_day4_bio rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BW
Sample
Accession:
GSM7996348
ID:
307996348
14.

U2OS_FOXA1FL_day4_bio rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996347
ID:
307996347
15.

U2OS_FOXA2dCTD_day4_biol rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BW
Sample
Accession:
GSM7996346
ID:
307996346
16.

U2OS_FOXA2dCTD_day4_biol rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996345
ID:
307996345
17.

U2OS_FOXA2FL_day4_biol rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BW
Sample
Accession:
GSM7996342
ID:
307996342
18.

U2OS_FOXA2FL_day4_biol rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data: BED, BW
Sample
Accession:
GSM7996341
ID:
307996341
19.

U2OS_Input

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE203644 GSE203650
Download data
Sample
Accession:
GSM7996338
ID:
307996338
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Supplemental Content

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