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Items: 12

1.

RIP-seq for SCML2 and SCML2 mutants in 293T-REx and K562 cells

(Submitter supplied) Polycomb repressive complex-1 (PRC1) is essential for the epigenetic regulation of gene expression. SCML2 is a mammalian homolog of Drosophila SCM, a Polycomb-group protein that associates with PRC1. Here, we show that SCML2A, an SCML2 isoform tightly associated to chromatin, contributes to PRC1 localization and also directly enforces repression of certain Polycomb target genes. SCML2A binds to PRC1 via its SPM domain and interacts with ncRNAs through a novel RNA-binding region (RBR). more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL11154
10 Samples
Download data: TXT, WIG
Series
Accession:
GSE38274
ID:
200038274

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10400 Series
180082 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

293Trex_N3-SCML2AdRBR.HA.PA

Organism:
Homo sapiens
Source name:
293T-REx
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data
Sample
Accession:
GSM1424796
ID:
301424796

SRA Run Selector

4.

293Trex_N3-SCML2A.HA.PA

Organism:
Homo sapiens
Source name:
293T-REx
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data
Sample
Accession:
GSM1424795
ID:
301424795

SRA Run Selector

5.

293Trex_N3.HA.PA

Organism:
Homo sapiens
Source name:
293T-REx
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data
Sample
Accession:
GSM1424794
ID:
301424794

SRA Run Selector

6.

293Trex.NE400.PA

Organism:
Homo sapiens
Source name:
293T-REx
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data
Sample
Accession:
GSM1424793
ID:
301424793

SRA Run Selector

7.

K562.PMA.SCML2.PA

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data: WIG
Sample
Accession:
GSM937878
ID:
300937878

SRA Run Selector

8.

K562.PMA.input.PA

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data: WIG
Sample
Accession:
GSM937877
ID:
300937877

SRA Run Selector

9.

K562.hemin.SCML2.PA

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data: WIG
Sample
Accession:
GSM937876
ID:
300937876

SRA Run Selector

10.

K562.hemin.input.PA

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data: WIG
Sample
Accession:
GSM937875
ID:
300937875

SRA Run Selector

11.

K562.DMSO.SCML2.PA

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data: WIG
Sample
Accession:
GSM937874
ID:
300937874

SRA Run Selector

12.

K562.DMSO.input.PA

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL11154
Series:
GSE38274 GSE38275
Download data: WIG
Sample
Accession:
GSM937873
ID:
300937873

SRA Run Selector

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