GSE44585[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2000445851.

RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma

(Submitter supplied) During development neuronal progenitors compete for growth factors such as nerve growth factor NGF and require the prolyl hydroxylase EglN3 and the kinesin KIF1Bβ for developmental apoptosis. Inherited KIF1Bβ loss-of-function mutations in neuroblastomas and pheochromocytomas implicate KIF1Bβ as a 1p36.2 tumor suppressor, however the mechanism of tumor suppression is unknown. We found that KIF1Bβ interacts with the RNA helicase A (DHX9) resulting in DHX9 nuclear accumulation to regulate apoptosis. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
12 Samples

Download data: BED, TXT

Series

Accession:: GSE44585

ID:: 200044585

PubMed Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10400 Series
180082 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3010872683.

NB1 shDHX9 KIF1Bbeta biol repl C

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087268

ID:: 301087268

SRA Run Selector

Select item 3010872674.

NB1 shDHX9 KIF1Bbeta biol repl B

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087267

ID:: 301087267

SRA Run Selector

Select item 3010872665.

NB1 shDHX9 KIF1Bbeta biol repl A

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087266

ID:: 301087266

SRA Run Selector

Select item 3010872656.

NB1 shDHX9 controlplasmid biol repl C

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087265

ID:: 301087265

SRA Run Selector

Select item 3010872647.

NB1 shDHX9 controlplasmid biol repl B

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087264

ID:: 301087264

SRA Run Selector

Select item 3010872638.

NB1 shDHX9 controlplasmid biol repl A

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087263

ID:: 301087263

SRA Run Selector

Select item 3010872629.

NB1 shSCR KIF1Bbeta biol repl C

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087262

ID:: 301087262

SRA Run Selector

Select item 30108726110.

NB1 shSCR KIF1Bbeta biol repl B

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087261

ID:: 301087261

SRA Run Selector

Select item 30108726011.

NB1 shSCR KIF1Bbeta biol repl A

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087260

ID:: 301087260

SRA Run Selector

Select item 30108725912.

NB1 shSCR controlplasmid biol repl C

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087259

ID:: 301087259

SRA Run Selector

Select item 30108725813.

NB1 shSCR controlplasmid biol repl B

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087258

ID:: 301087258

SRA Run Selector

Select item 30108725714.

NB1 shSCR controlplasmid biol repl A

Organism:: Homo sapiens

Source name:: NB1 cell line

Platform:: GPL11154
Series:: GSE44585

Download data: BED, TXT

Sample

Accession:: GSM1087257

ID:: 301087257

SRA Run Selector

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