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Items: 5

1.

Amplitude modulation of androgen signaling by c-MYC [RNA-Seq]

(Submitter supplied) Androgen-stimulated growth of the molecular apocrine breast cancer is mediated by an androgen receptor (AR)-regulated transcriptional program. Through profiling the genomic licalizations of AR and its co-regulators FOXA1 and TCF7L2 in MDA-MB-453 breast cancer cells, we revealed the molecular details of the AR-centered regulatory network. We further identified that c-MYC is a key downstream target co-regulated by AR, FOXA1 and TCF7L2, and reinforces the transctiopnal activation of androgen-responsive genes in this subtype of breast cancers.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
3 Samples
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Series
Accession:
GSE45202
ID:
200045202

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10400 Series
180082 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

MDA-MB-453 siMYC-DHT

Organism:
Homo sapiens
Source name:
MDA-MB-453 cells transfected with MYC siRNA followed by DHT treatment
Platform:
GPL11154
Series:
GSE45202 GSE45203
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Sample
Accession:
GSM1099037
ID:
301099037

SRA Run Selector

4.

MDA-MB-453 siCtrl-DHT

Organism:
Homo sapiens
Source name:
MDA-MB-453 cells transfected with control siRNA followed by DHT treatment
Platform:
GPL11154
Series:
GSE45202 GSE45203
Download data
Sample
Accession:
GSM1099036
ID:
301099036

SRA Run Selector

5.

MDA-MB-453 siCtrl-veh

Organism:
Homo sapiens
Source name:
MDA-MB-453 cells transfected with control siRNA followed by vehicle treatment
Platform:
GPL11154
Series:
GSE45202 GSE45203
Download data
Sample
Accession:
GSM1099035
ID:
301099035

SRA Run Selector

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