U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 12

1.

Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency 

(Submitter supplied) Constitutive low level DNA damage is linked to innate immune activation. Hierarchical clustering of over 9000 transcripts revealed remarkably similar profiles in a patient with lupus erythematosus and a patient with AGS with up-regulation of genes involved in DNA damage signaling, p53-inducible genes, senescence-associated genes as well as up-regulation of interferon-stimulated genes. Transcriptional profiling of fibroblasts exposed to oxidative stress showed a marked up-regulation of genes involved in DNA replication/repair and replication licensing in TREX1-deficient cells compared to wild type cells suggesting massive replication stress.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
10 Samples
Download data: XLSX
Series
Accession:
GSE59233
ID:
200059233

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11830 Series
336732 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

AGS1 [L2549_H2O2]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431065
ID:
301431065

SRA Run Selector

4.

AGS1 [L2548]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431064
ID:
301431064

SRA Run Selector

5.

SLE1 [L2551_H2O2]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431063
ID:
301431063

SRA Run Selector

6.

SLE1 [L2550]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431062
ID:
301431062

SRA Run Selector

7.

WT2 [L2547_H2O2]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431061
ID:
301431061

SRA Run Selector

8.

WT1 [L2546_H2O2]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431060
ID:
301431060

SRA Run Selector

9.

WT2 [L2553]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431059
ID:
301431059

SRA Run Selector

10.

WT1 [L2545]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431058
ID:
301431058

SRA Run Selector

11.

WT2 [L2248]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431057
ID:
301431057

SRA Run Selector

12.

WT1 [L2244]

Organism:
Homo sapiens
Source name:
fibroblast
Platform:
GPL16791
Series:
GSE59233
Download data
Sample
Accession:
GSM1431056
ID:
301431056

SRA Run Selector

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSE59233[Accession]|query=1|qty=2|blobid=MCID_665342d06c053549898aea36|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center