GSE69558[Accession] - GEO DataSets - NCBI

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Select item 2000695581.

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma [ChIP-Seq]

(Submitter supplied) B-cell lymphomas frequently demonstrate inter-chromosomal translocations that lead to oncogene activation by heterologous distal regulatory elements. We utilized a novel approach, termed ‘Pinpointing of Enhancer-Associated Rearrangements by Chromatin Immunoprecipitation’ or PEAR-ChIP, to simultaneously map enhancer activity and proximal rearrangements in lymphoma cell lines and patient biopsies. The method efficiently detects rearrangements within and adjacent to known cancer genes such as CCND1, BCL2, MYC, PDCD1LG2, NOTCH1, CIITA, and SGK1, as well as novel enhancer duplication events of likely oncogenic significance. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL18573 GPL16791
70 Samples

Download data: TDF

Series

Accession:: GSE69558

ID:: 200069558

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000185732.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

11973 Series
329582 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 1000167913.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

11813 Series
336528 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3017039604.

Organism:: Homo sapiens

Source name:: SLL-03 Input

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703960

ID:: 301703960

SRA Run Selector

Select item 3017039595.

Organism:: Homo sapiens

Source name:: SLL-03 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703959

ID:: 301703959

SRA Run Selector

Select item 3017039586.

Organism:: Homo sapiens

Source name:: SLL-02 Input

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703958

ID:: 301703958

SRA Run Selector

Select item 3017039577.

Organism:: Homo sapiens

Source name:: SLL-02 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703957

ID:: 301703957

SRA Run Selector

Select item 3017039568.

Organism:: Homo sapiens

Source name:: SLL-01 Input

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703956

ID:: 301703956

SRA Run Selector

Select item 3017039559.

Organism:: Homo sapiens

Source name:: SLL-01 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703955

ID:: 301703955

SRA Run Selector

Select item 30170394610.

Organism:: Homo sapiens

Source name:: HGB-07 Input

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703946

ID:: 301703946

SRA Run Selector

Select item 30170394511.

Organism:: Homo sapiens

Source name:: HGB-07 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703945

ID:: 301703945

SRA Run Selector

Select item 30170394412.

Organism:: Homo sapiens

Source name:: HGB-06 Input

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703944

ID:: 301703944

SRA Run Selector

Select item 30170394313.

Organism:: Homo sapiens

Source name:: HGB-06 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703943

ID:: 301703943

SRA Run Selector

Select item 30170394214.

Organism:: Homo sapiens

Source name:: HGB-05 Input

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703942

ID:: 301703942

SRA Run Selector

Select item 30170394115.

Organism:: Homo sapiens

Source name:: HGB-05 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703941

ID:: 301703941

SRA Run Selector

Select item 30170392516.

Organism:: Homo sapiens

Source name:: REC-1 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703925

ID:: 301703925

SRA Run Selector

Select item 30170391817.

OCI-LY-7 H3K27ac

Organism:: Homo sapiens

Source name:: OCI-LY-7 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703918

ID:: 301703918

SRA Run Selector

Select item 30170391418.

OCI-LY-1 H3K27ac

Organism:: Homo sapiens

Source name:: OCI-LY-1 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703914

ID:: 301703914

SRA Run Selector

Select item 30170391219.

Organism:: Homo sapiens

Source name:: MINO H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703912

ID:: 301703912

SRA Run Selector

Select item 30170390920.

KARPAS-422 H3K27ac

Organism:: Homo sapiens

Source name:: KARPAS-422 H3K27ac

Platform:: GPL18573
Series:: GSE69558

Download data: TDF

Sample

Accession:: GSM1703909

ID:: 301703909

SRA Run Selector

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