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Items: 9

1.

CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

(Submitter supplied) Spatial genome organization and its effect on transcription remains a fundamental biological question. We applied an advanced ChIA-PET strategy to comprehensively map higher-order chromosome folding and chromatin interactions mediated by CTCF and RNAPII with haplotype specificity and nucleotide resolution in different human cell lineages. We find that CTCF-mediated interaction anchors serve as structural foci for spatial organization of constitutive genes concordant with CTCF-motif orientation, whereas RNAPII interacts within these structures by selectively drawing cell-type-specific genes towards CTCF-foci and forming RNAPII foci for coordinated transcription. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL16791 GPL18573
6 Samples
Download data: BW, TXT
Series
Accession:
GSE72816
ID:
200072816

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12044 Series
332532 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11877 Series
340477 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

4.

GM12878_SMC3_nexus

Organism:
Homo sapiens
Source name:
GM12878
Platform:
GPL18573
Series:
GSE72816
Download data: BW
Sample
Accession:
GSM1872891
ID:
301872891

SRA Run Selector

5.

GM12878_RAD21_nexus

Organism:
Homo sapiens
Source name:
GM12878
Platform:
GPL18573
Series:
GSE72816
Download data: BW
Sample
Accession:
GSM1872890
ID:
301872890

SRA Run Selector

6.

HeLa_RNAPII

Organism:
Homo sapiens
Source name:
HeLa-S3
Platform:
GPL18573
Series:
GSE72816
Download data: TXT
Sample
Accession:
GSM1872889
ID:
301872889

SRA Run Selector

7.

HeLa_CTCF

Organism:
Homo sapiens
Source name:
HeLa-S3
Platform:
GPL16791
Series:
GSE72816
Download data: TXT
Sample
Accession:
GSM1872888
ID:
301872888

SRA Run Selector

8.

GM12878_RNAPII

Organism:
Homo sapiens
Source name:
GM12878
Platform:
GPL16791
Series:
GSE72816
Download data: TXT
Sample
Accession:
GSM1872887
ID:
301872887

SRA Run Selector

9.

GM12878_CTCF

Organism:
Homo sapiens
Source name:
GM12878
Platform:
GPL16791
Series:
GSE72816
Download data: TXT
Sample
Accession:
GSM1872886
ID:
301872886

SRA Run Selector

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