GSE74141[Accession] - GEO DataSets - NCBI

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Select item 2000741411.

NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation

(Submitter supplied) The PARP family of proteins comprises 17 members, about two thirds of which are active mono- or poly(ADP-ribosyl)transferase enzymes that transfer the ADP-ribose moiety of NAD+ onto target proteins. In many cases, ADP-ribosylation, which plays critical roles in human diseases (e.g., cancer, heart disease, and neuropathies) is associated with abrogation of the molecular functions of the target. Discerning ADP-ribosylation events mediated by a specific PARP is challenging, since all PARPs use the same substrate (i.e., NAD+) and the available inhibitors lack the specificity needed to make such conclusions. more...

Organism:: Homo sapiens; Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13112 GPL18573
66 Samples

Download data: BED

Series

Accession:: GSE74141

ID:: 200074141

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000185732.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

12044 Series
332532 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 1000131123.

Illumina HiSeq 2000 (Mus musculus)

Organism:: Mus musculus

8244 Series
187377 Samples

Platform

Accession:: GPL13112

ID:: 100013112

Select item 3019111834.

click-ChIP-seq_MEF_2

Organism:: Mus musculus

Source name:: MEF, click-ChIP-seq

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911183

ID:: 301911183

SRA Run Selector

Select item 3019111825.

click-ChIP-seq_MEF_1

Organism:: Mus musculus

Source name:: MEF, click-ChIP-seq

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911182

ID:: 301911182

SRA Run Selector

Select item 3019111816.

click-ChIP-seq_Input_MEF_2

Organism:: Mus musculus

Source name:: MEF, Input

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911181

ID:: 301911181

SRA Run Selector

Select item 3019111807.

click-ChIP-seq_Input_MEF_1

Organism:: Mus musculus

Source name:: MEF, Input

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911180

ID:: 301911180

SRA Run Selector

Select item 3019111798.

PARP-1_ChIP-seq_MEF_2

Organism:: Mus musculus

Source name:: MEF, PARP-1

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911179

ID:: 301911179

SRA Run Selector

Select item 3019111789.

PARP-1_ChIP-seq_MEF_1

Organism:: Mus musculus

Source name:: MEF, PARP-1

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911178

ID:: 301911178

SRA Run Selector

Select item 30191117710.

ChIP-seq_Input_MEF_2

Organism:: Mus musculus

Source name:: MEF, Input

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911177

ID:: 301911177

SRA Run Selector

Select item 30191117611.

ChIP-seq_Input_MEF_1

Organism:: Mus musculus

Source name:: MEF, Input

Platform:: GPL13112
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM1911176

ID:: 301911176

SRA Run Selector

Select item 30215168312.

NELF-EKD_VEH_flagNELF-Emutant_PolII_2

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Emutant, PolII

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151683

ID:: 302151683

SRA Run Selector

Select item 30215168213.

NELF-EKD_VEH_flagNELF-Emutant_PolII_1

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Emutant, PolII

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151682

ID:: 302151682

SRA Run Selector

Select item 30215168114.

NELF-EKD_VEH_flagNELF-Ewildtype_PolII_2

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Ewildtype, PolII

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151681

ID:: 302151681

SRA Run Selector

Select item 30215168015.

NELF-EKD_VEH_flagNELF-Ewildtype_PolII_1

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Ewildtype, PolII

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151680

ID:: 302151680

SRA Run Selector

Select item 30215167916.

NELF-EKD_VEH_GFP_PolII_2

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, GFP, PolII

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151679

ID:: 302151679

SRA Run Selector

Select item 30215167817.

NELF-EKD_VEH_GFP_PolII_1

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, GFP, PolII

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151678

ID:: 302151678

SRA Run Selector

Select item 30215167718.

NELF-EKD_VEH_flagNELF-Emutant_FLAG_2

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Emutant, FLAG

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151677

ID:: 302151677

SRA Run Selector

Select item 30215167619.

NELF-EKD_VEH_flagNELF-Emutant_FLAG_1

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Emutant, FLAG

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151676

ID:: 302151676

SRA Run Selector

Select item 30215167520.

NELF-EKD_VEH_flagNELF-Ewildtype_FLAG_2

Organism:: Homo sapiens

Source name:: NELF-E Knockdown, vehicle, flagNELF-Ewildtype, FLAG

Platform:: GPL18573
Series:: GSE74141

Download data: BED

Sample

Accession:: GSM2151675

ID:: 302151675

SRA Run Selector

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