GSE74142[Accession] - GEO DataSets - NCBI

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Items: 18

Select item 2000741421.

NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation

(Submitter supplied) The PARP family of proteins comprises 17 members, about two thirds of which are active mono- or poly(ADP-ribosyl)transferase enzymes that transfer the ADP-ribose moiety of NAD+ onto target proteins. In many cases, ADP-ribosylation, which plays critical roles in human diseases (e.g., cancer, heart disease, and neuropathies) is associated with abrogation of the molecular functions of the target. Discerning ADP-ribosylation events mediated by a specific PARP is challenging, since all PARPs use the same substrate (i.e., NAD+) and the available inhibitors lack the specificity needed to make such conclusions. more...

Organism:: Homo sapiens

Type:: Other; Expression profiling by high throughput sequencing

Platforms:: GPL9052 GPL18573
15 Samples

Download data: BED, BW

Series

Accession:: GSE74142

ID:: 200074142

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000185732.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

12045 Series
332544 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 1000090523.

Illumina Genome Analyzer (Homo sapiens)

Organism:: Homo sapiens

586 Series
7896 Samples

Platform

Accession:: GPL9052

ID:: 100009052

Select item 3050656494.

PARP-1 KD_GRO-seq_E2 rep2

Organism:: Homo sapiens

Source name:: MCF-7

Platform:: GPL9052
Series:: GSE74142

Sample

Accession:: GSM5065649

ID:: 305065649

SRA Run Selector

Select item 3050656485.

PARP-1 KD_GRO-seq_E2 rep1

Organism:: Homo sapiens

Source name:: MCF-7

Platform:: GPL9052
Series:: GSE74142

Sample

Accession:: GSM5065648

ID:: 305065648

SRA Run Selector

Select item 3050656476.

Luc KD_GRO-seq_E2 rep2

Organism:: Homo sapiens

Source name:: MCF-7

Platform:: GPL9052
Series:: GSE74142

Sample

Accession:: GSM5065647

ID:: 305065647

SRA Run Selector

Select item 3050656467.

Luc KD_GRO-seq_E2 rep1

Organism:: Homo sapiens

Source name:: MCF-7

Platform:: GPL9052
Series:: GSE74142

Sample

Accession:: GSM5065646

ID:: 305065646

SRA Run Selector

Select item 3021516848.

GRO-seq_LucKD_PJ34_MCF7

Organism:: Homo sapiens

Source name:: GRO-seq in MCF7 cells with shRNA-mediated knockdown of Luciferase as a control with 1 hour 1 µM PJ34 Treatment

Platform:: GPL9052
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151684

ID:: 302151684

SRA Run Selector

Select item 3019111879.

GRO-seq_PARP-1KD_Veh_MCF7_2

Organism:: Homo sapiens

Source name:: GRO-seq in vehicle treated MCF7 cells with shRNA-mediated knockdown of PARP-1

Platform:: GPL9052
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM1911187

ID:: 301911187

SRA Run Selector

Select item 30191118610.

GRO-seq_PARP-1KD_Veh_MCF7_1

Organism:: Homo sapiens

Source name:: GRO-seq in vehicle treated MCF7 cells with shRNA-mediated knockdown of PARP-1

Platform:: GPL9052
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM1911186

ID:: 301911186

SRA Run Selector

Select item 30191118511.

GRO-seq_LucKD_Veh_MCF-7_2

Organism:: Homo sapiens

Source name:: GRO-seq in vehicle treated MCF7 cells with shRNA-mediated knockdown of Luciferase as a control

Platform:: GPL9052
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM1911185

ID:: 301911185

SRA Run Selector

Select item 30191118412.

GRO-seq_LucKD_Veh_MCF-7_1

Organism:: Homo sapiens

Source name:: GRO-seq in vehicle treated MCF7 cells with shRNA-mediated knockdown of Luciferase as a control

Platform:: GPL9052
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM1911184

ID:: 301911184

SRA Run Selector

Select item 30215169013.

RNA-seq_PARP-1KD_MCF7_2

Organism:: Homo sapiens

Source name:: RNA-seq in MCF7 cells with shRNA-mediated knockdown of PARP-1

Platform:: GPL18573
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151690

ID:: 302151690

SRA Run Selector

Select item 30215168914.

RNA-seq_PARP-1KD_MCF7_1

Organism:: Homo sapiens

Source name:: RNA-seq in MCF7 cells with shRNA-mediated knockdown of PARP-1

Platform:: GPL18573
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151689

ID:: 302151689

SRA Run Selector

Select item 30215168815.

RNA-seq_LucKD_DRB_MCF7_2

Organism:: Homo sapiens

Source name:: RNA-seq in MCF7 cells with shRNA-mediated knockdown of Luciferase as a control with 3 hours 100 µM DRB treatment

Platform:: GPL18573
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151688

ID:: 302151688

SRA Run Selector

Select item 30215168716.

RNA-seq_LucKD_DRB_MCF7_1

Organism:: Homo sapiens

Source name:: RNA-seq in MCF7 cells with shRNA-mediated knockdown of Luciferase as a control with 3 hours 100 µM DRB treatment

Platform:: GPL18573
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151687

ID:: 302151687

SRA Run Selector

Select item 30215168617.

RNA-seq_LucKD_MCF7_2

Organism:: Homo sapiens

Source name:: RNA-seq in MCF7 cells with shRNA-mediated knockdown of Luciferase as a control

Platform:: GPL18573
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151686

ID:: 302151686

SRA Run Selector

Select item 30215168518.

RNA-seq_LucKD_MCF7_1

Organism:: Homo sapiens

Source name:: RNA-seq in MCF7 cells with shRNA-mediated knockdown of Luciferase as a control

Platform:: GPL18573
Series:: GSE74142

Download data: BED

Sample

Accession:: GSM2151685

ID:: 302151685

SRA Run Selector

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