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Items: 1 to 20 of 23

1.

Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Bulk RNA-Seq validation

(Submitter supplied) Transcriptional enhancers orchestrate cell-type specific gene expression programs critical to eukaryotic development, physiology, and disease. However, despite the large number of enhancers now identified, only a small number have been functionally assessed. Here, we develop MOsaic Single-cell Analysis by Indexed CRISPR Sequencing (Mosaic-seq), a method that measures one direct phenotype of enhancer repression: change of the transcriptome, at the single cell level. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
21 Samples
Download data: TXT
Series
Accession:
GSE81412
ID:
200081412
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

K562, dCas9-KRAB, infected with sgRNA64 (rep5); treated with TNFalpha for 1h

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544709
ID:
302544709
4.

K562, dCas9-KRAB, infected with sgRNA64 (rep4); treated with TNFalpha for 1h

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544708
ID:
302544708
5.

K562, dCas9-KRAB, infected with sgRNA64 (rep3); treated with TNFalpha for 1h

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544707
ID:
302544707
6.

K562, dCas9-KRAB, infected with sgRNA64 (rep2); treated with TNFalpha for 1h

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544706
ID:
302544706
7.

K562, dCas9-KRAB, infected with sgRNA64 (rep1); treated with TNFalpha for 1h

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544705
ID:
302544705
8.

K562, dCas9-KRAB, infected with sgRNA63 (rep5)

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544704
ID:
302544704
9.

K562, dCas9-KRAB, infected with sgRNA63 (rep4)

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544703
ID:
302544703
10.

K562, dCas9-KRAB, infected with sgRNA63 (rep3)

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544702
ID:
302544702
11.

K562, dCas9-KRAB, infected with sgRNA63 (rep2)

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544701
ID:
302544701
12.

K562, dCas9-KRAB, infected with sgRNA63 (rep1)

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2544700
ID:
302544700
13.

K562 dCas9-KRAB, not infected

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152032
ID:
302152032
14.

K562 dCas9-KRAB, Lenti-sgRNA82_bc29

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152031
ID:
302152031
15.

K562 dCas9-KRAB, Lenti-sgRNA80_bc24

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152030
ID:
302152030
16.

K562 dCas9-KRAB, Lenti-sgRNA63_bc38

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152029
ID:
302152029
17.

K562 dCas9-KRAB, Lenti-sgRNA62_bc37

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152028
ID:
302152028
18.

K562 dCas9-KRAB, Lenti-sgRNA60_bc35

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152027
ID:
302152027
19.

K562 dCas9-KRAB, Lenti-sgRNA59_bc33

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152026
ID:
302152026
20.

K562 dCas9-KRAB, Lenti-sgRNA57_bc19

Organism:
Homo sapiens
Source name:
K562 cells
Platform:
GPL18573
Series:
GSE81412 GSE81884
Download data: TXT
Sample
Accession:
GSM2152025
ID:
302152025
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