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Items: 1 to 20 of 68

1.

Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (RNA-seq)

(Submitter supplied) Targeting the dysregulated BRaf-MEK-ERK pathway in cancer has increasingly emerged in clinical trial design. Despite clinical responses in specific cancers using inhibitors targeting BRaf and MEK, resistance develops often involving non-genomic adaptive bypass mechanisms. Inhibition of MEK1/2 by trametinib in triple negative breast cancer (TNBC) patients induced dramatic transcriptional responses, including upregulation of receptor tyrosine kinases (RTKs) comparing tumor samples before and after one week of treatment. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL13112 GPL18573
64 Samples
Download data: CSV, TXT, XLSX
Series
Accession:
GSE87419
ID:
200087419

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12045 Series
332544 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8244 Series
187377 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

4.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10425 Series
180579 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

5.

SUM159_DMSO_24h_500nMtrametinib_replicate2

Organism:
Homo sapiens
Source name:
SUM159_DMSO_24h_500nMtrametinib
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2462678
ID:
302462678

SRA Run Selector

6.

SUM159_DMSO_24h_500nMtrametinib_replicate1

Organism:
Homo sapiens
Source name:
SUM159_DMSO_24h_500nMtrametinib
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2462677
ID:
302462677

SRA Run Selector

7.

WHIM12_500nMtrametinib_24h_replicate2

Organism:
Homo sapiens
Source name:
WHIM12_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459932
ID:
302459932

SRA Run Selector

8.

WHIM12_500nMtrametinib_24h_replicate1

Organism:
Homo sapiens
Source name:
WHIM12_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459931
ID:
302459931

SRA Run Selector

9.

WHIM12_DMSO_24h_replicate2

Organism:
Homo sapiens
Source name:
WHIM12_DMSO_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459930
ID:
302459930

SRA Run Selector

10.

WHIM12_DMSO_24h_replicate1

Organism:
Homo sapiens
Source name:
WHIM12_DMSO_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459929
ID:
302459929

SRA Run Selector

11.

HS578T_500nMtrametinib_24h_replicate2

Organism:
Homo sapiens
Source name:
HS578T_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459928
ID:
302459928

SRA Run Selector

12.

HS578T_500nMtrametinib_24h_replicate1

Organism:
Homo sapiens
Source name:
HS578T_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459927
ID:
302459927

SRA Run Selector

13.

HS578T_DMSO_24h_replicate2

Organism:
Homo sapiens
Source name:
HS578T_DMSO_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459926
ID:
302459926

SRA Run Selector

14.

HS578T_DMSO_24h_replicate1

Organism:
Homo sapiens
Source name:
HS578T_DMSO_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459925
ID:
302459925

SRA Run Selector

15.

SUM159_500nMtrametinib_24h_replicate2

Organism:
Homo sapiens
Source name:
SUM159_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459924
ID:
302459924

SRA Run Selector

16.

SUM159_500nMtrametinib_24h_replicate1

Organism:
Homo sapiens
Source name:
SUM159_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459923
ID:
302459923

SRA Run Selector

17.

MDAMB468_500nMtrametinib_24h_replicate2

Organism:
Homo sapiens
Source name:
MDAMB468_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459922
ID:
302459922

SRA Run Selector

18.

MDAMB468_500nMtrametinib_24h_replicate1

Organism:
Homo sapiens
Source name:
MDAMB468_500nMtrametinib_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459921
ID:
302459921

SRA Run Selector

19.

MDAMB468_DMSO_24h_replicate2

Organism:
Homo sapiens
Source name:
MDAMB468_DMSO_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459920
ID:
302459920

SRA Run Selector

20.

MDAMB468_DMSO_24h_replicate1

Organism:
Homo sapiens
Source name:
MDAMB468_DMSO_24h
Platform:
GPL18573
Series:
GSE87419 GSE87424
Download data: CSV
Sample
Accession:
GSM2459919
ID:
302459919

SRA Run Selector

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db=gds|term=GSE87419[Accession]|query=1|qty=3|blobid=MCID_666bbd9e909a3d46ad82ccb1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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