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Items: 18

1.

Inhibition of endothelial Notch signaling attenuates inflammation [ChIP-Seq]

(Submitter supplied) Vascular endothelial cells upregulate the Notch ligand Jagged1 in response to inflammatory activation. Here we show that abrogation of endothelial Notch1 signaling impairs induction of key inflammatory target genes. Accordingly, inducible endothelial-targeted knockout of the canonical Notch transcription factor RBPJ reduces inflammation in a murine model of contact hypersensitivity, while overexpression of constitutive active Notch1 has the opposite effect. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL20301
15 Samples
Download data: BED, BW
Series
Accession:
GSE87552
ID:
200087552

PubMed Similar studies SRA Run Selector

2.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8141 Series
186983 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

3.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12044 Series
332532 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

4.

HUVEC_Notch1_RBPJ_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL20301
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333691
ID:
302333691

SRA Run Selector

5.

HUVEC_UT_RBPJ

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL20301
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333678
ID:
302333678

SRA Run Selector

6.

HUVEC_UT_Notch1

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL20301
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333677
ID:
302333677

SRA Run Selector

7.

HUVEC_Notch1kd_IL1beta_FA_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333690
ID:
302333690

SRA Run Selector

8.

HUVEC_Scr_IL1beta_FA_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333689
ID:
302333689

SRA Run Selector

9.

HUVEC_Scr_FA_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333688
ID:
302333688

SRA Run Selector

10.

HUVEC_Notch1kd_IL1beta_DSG_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333687
ID:
302333687

SRA Run Selector

11.

HUVEC_Scr_IL1beta_DSG_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333686
ID:
302333686

SRA Run Selector

12.

HUVEC_Scr_DSG_Input

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BW
Sample
Accession:
GSM2333685
ID:
302333685

SRA Run Selector

13.

HUVEC_Notch1kd_IL1beta_H3K27ac

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333684
ID:
302333684

SRA Run Selector

14.

HUVEC_Scr_IL1beta_H3K27ac

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333683
ID:
302333683

SRA Run Selector

15.

HUVEC_Scr_H3K27ac

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333682
ID:
302333682

SRA Run Selector

16.

HUVEC_Notch1kd_IL1beta_RelA

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333681
ID:
302333681

SRA Run Selector

17.

HUVEC_Scr_IL1beta_RelA

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333680
ID:
302333680

SRA Run Selector

18.

HUVEC_Scr_RelA

Organism:
Homo sapiens
Source name:
Human umbilical vein endothelial cells (HUVECs)
Platform:
GPL18573
Series:
GSE85987 GSE87552
Download data: BED, BW
Sample
Accession:
GSM2333679
ID:
302333679

SRA Run Selector

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