GSM1035434[Accession] - GEO DataSets

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Items: 4

Select item 2000422131.

SUMO is an Integral and Instructive Component of Chromatin in Cell Growth and Senescence

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL10999
26 Samples

Download data: BED, WIG

Series

Accession:: GSE42213

ID:: 200042213

PubMed Full text in PMC Similar studies

Select item 2000422112.

Genome wide occupancy of SUMO machinery in proliferative and Ras-induced senescent human primary fibroblasts

(Submitter supplied) Transcription factors represent one of the largest groups of proteins regulated by SUMO, and their modification has generally been correlated with transcriptional repression. However, as most of the studies focus on specific sumoylated transcriptional regulators, the distribution and global role of SUMO on chromatin in relation to transcription regulation remain largely unknown. To investigate this role, we determined the occupancy of SUMO machinery proteins on chromatin by ChIP coupled to sequencing in human primary cells.