GSM1143125[Accession] - GEO DataSets

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Items: 4

Select item 2000548921.

LRH-1 governs vital transcriptional programs in endocrine sensitive and resistant breast cancer cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL11154 GPL10558
16 Samples

Download data: WIG

Series

Accession:: GSE54892

ID:: 200054892

Select item 2000470272.

LRH-1 governs vital transcriptional programs in endocrine sensitive and resistant breast cancer cells: LRH-1 ChIP-seq

(Submitter supplied) Tumor characteristics are decisive in the determination of treatment strategy for breast cancer patients. Patients with estrogen receptor a(ERa)-positive breast cancer can benefit from long-term hormonal treatment. Nonetheless, the majority of patients will develop resistance to these therapies. Here, we investigated the role of the nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in anti-estrogen (AE) sensitive and resistant breast cancer cells. more...