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Items: 4

1.

Lamin B1 depletion in senescent cells leads to large-scale changes in the chromatin landscape

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10999 GPL11154 GPL570
27 Samples
Download data: BW, CEL
Series
Accession:
GSE36641
ID:
200036641
2.

Lamin B1 Depletion in Senescent Cells Triggers Large-Scale Changes in Gene Expression and in the Chromatin Landscape [ expression array ]

(Submitter supplied) Cellular senescence is a stable proliferation arrest in response to stress, associated with an altered secretory pathway (Senescence Associated Secretory Phenotype (SASP)). Senescence-associated proliferation arrest and the SASP are thought to act in concert to promote tumor suppression and tissue aging. While chromatin regulation and down regulation of lamin B1 have been implicated as effectors of cell senescence, functional interactions between them are poorly understood. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
10 Samples
Download data: CEL
Series
Accession:
GSE36640
ID:
200036640
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5651 Series
61 Related Platforms
171341 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

IMR90-Proliferating-4

Organism:
Homo sapiens
Source name:
IMR90 fibroblasts_28 population doublings
Platform:
GPL570
Series:
GSE36640 GSE36641
Download data: CEL
Sample
Accession:
GSM897834
ID:
300897834
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