Similar studies for GEO DataSets (Select 200047539) - GEO DataSets

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Items: 2

Select item 2000475391.

Experimental characterization of the human non-sequence-specific nucleic acid interactome

(Submitter supplied) The interactions between proteins and nucleic acids have a fundamental function in many biological processes well beyond nuclear gene transcription and include RNA homeostasis, protein translation and pathogen sensing for innate immunity. While our knowledge of the ensemble of proteins binding individual mRNAs in mammalian cells has greatly been augmented by recent surveys, no systematic study on the native proteins of human cells differentially engaging various types of nucleic acids in a non sequence-specific manner has been reported. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
2 Samples

Download data: TXT, WIG

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Accession:: GSE47539

ID:: 200047539

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000986522.

Quantitative analysis of the DNA methylation sensitivity of transcription factor complexes

(Submitter supplied) EpiSELEX-seq method was used to characterize the binding preference of human TF complexes to methylated DNA, including BZIP proteins ATF4 and CEBPb, homeodomain TF heterodimers of HM(Meis1)-Pbx1 together with either HoxA1, HoxA5 or HoxA9 and tumor suppressor protein p53.