Similar studies for GEO DataSets (Select 200235626) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from GEO DataSets

Items: 2

Select item 2002356261.

Association of inflammatory mediators with mitochondrial DNA mutations in geriatric COVID-19 patients

(Submitter supplied) This study aimed to evaluate single nucleotide substitutions in mtDNA and analyze their correlation with inflammatory biomarkers in elderly COVID-19 patients. A total of 30 COVID-19 patients and 33 older adult controls (aged over 65 years) were enrolled. mtDNA was extracted from buffy coat samples and sequenced using a chip-based resequencing system (Affymetrix MitoChip v2.0) which detects both homoplasmic and heteroplasmic mtDNA mutations, and allows the assessment of low-level heteroplasmy. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL10983
63 Samples

Download data: CEL, CHP

Series

Accession:: GSE235626

ID:: 200235626

PubMed Similar studies

Select item 2001137042.

Mitochondrial DNA allelic substitutions in Parkinson’s disease

(Submitter supplied) Mitochondrial DNA (mtDNA) damage is considered as a possible primary cause of Parkinson’s disease (PD). To explore the issue, mtDNA sequences from whole blood were analyzed in PD patients and controls using a resequencing chip and allelic substitutions were estimated for each nucleotide position (np) along the entire mtDNA sequence. Overall, 58 np showed a different allelic distribution in the two groups; of these, 81% showed an increase of non-reference alleles in PD patients, similar to findings reported in patients with Alzheimer’s disease, albeit in reduced proportion. more...