Histone lactylation antagonizes Senescent via facilitating gene-expression reprogramming [RNA-seq]

Histone lactylation antagonizes senescence via facilitating gene-expression reprogramming.

Histone lactylation antagonizes Senescent via facilitating gene-expression reprogramming [RNA-Seq II]

Small-molecule inhibition of PRMT5 activates p53 in erythropoiesis through perturbation of mRNA processing, transport and protein translation

CRIPSR screen identified CLEC16A suppresses astrocyte inflammasome-involved pathology via mitophagy

HMGA1 Chromatin Regulators Drive MPN Progression

Metabolic reprogramming from fatty acid oxidation to glycolysis in a patient mutation knock-in mouse model of Barth Syndrome.

Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance

Refine regulatory elements across the genome

Polycomb Deficiency Drives a FOXP2-high Aggressive State Targetable by Epigenetic Inhibitors

Total RNA-seq from Patient-Derived Xenograft models of Breast Cancer developed at Baylor College of Medicine

BCL6 is regulated by the RAS/MAPK/ELK axis and promotes KRAS-driven lung cancers

Alphavirus infection triggers antiviral RNAi immunity in mammals

Single-cell multi-omics in human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.

Single-cell analysis of gene networks in trophoectoderm and inner cell mass during human, monkey and mouse preimplantation development

Multi-omic analysis of cell-of-origin and epigenomic state in pediatric H3K27M gliomas

Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

Transcriptional landscape of oncogenic PI3K

Phosphorylated MED1 Links Transcription Recycling and Cancer Growth

Distinct N6-methyladenosine (m6A) Regulation of Innate Immune Responses During Bacterial and Viral Infections I