Histone lactylation antagonizes Senescent via facilitating gene-expression reprogramming [RNA-seq]

Histone lactylation antagonizes senescence via facilitating gene-expression reprogramming.

Histone lactylation antagonizes Senescent via facilitating gene-expression reprogramming [RNA-Seq II]

IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

Super cChIP-seq, a robust and universal epigenetic profiling method using 10 cells

Small-molecule inhibition of PRMT5 activates p53 in erythropoiesis through perturbation of mRNA processing, transport and protein translation

Extracellular niche and tumor microenvironment enhance the impact of KRAS inhibitors in pancreatic cancer models.

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion [ATAC-seq]

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.

BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites.

Bone Stromal Glutamine Renders Tumor cell PARP Inhibitor Resistance

CRIPSR screen identified CLEC16A suppresses astrocyte inflammasome-involved pathology via mitophagy

HMGA1 Chromatin Regulators Drive MPN Progression

Circulating cell-free, methylated DNA reveals tissue-specific, cellular damage from radiation treatment

Metabolic reprogramming from fatty acid oxidation to glycolysis in a patient mutation knock-in mouse model of Barth Syndrome.

Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility

Investigation of mettl4 mediated alterative splicing variation

Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance

Refine regulatory elements across the genome

G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions. Nat Genet (2023). https://doi.org/10.1038/s41588-023-01437-4