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| Status |
Public on Feb 15, 2018 |
| Title |
Wild type and Zbtb7b knockout mouse brown adipose tissue |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Zbtb7b is a zinc finger and BTB domain containing transcription factor that activates the thermogenic gene program during brown and beige adipocyte differentiation. Zbtb7b interacts with the long noncoding RNA Blnc1 and hnRNPU to form a ribonucleoprotein transcriptional complex
We used microarray to determine how Zbtb7b regulates brown fat gene expression at ambient room temperature and following cold exposure
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| Overall design |
Wild type and Zbtb7b knockout mice of 10 weeks of age were kept at ambient room temperature (22C) or following cold exposure at 4C for 4 hrs. Brown adipose tissue was harvested for total RNA isolation and microarray analysis.
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| Contributor(s) |
Li S, Lin JD |
| Citation(s) |
28784777 |
| Submission date |
Jul 07, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Jiandie Lin |
| E-mail(s) |
jdlin@umich.edu
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| Phone |
734-615-3512
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| Organization name |
University of Michigan
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| Department |
Life Sciences Institute
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| Street address |
210 Washtenaw Avenue
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| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
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| Platforms (1) |
| GPL17400 |
[MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (12)
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| GSM2696488 |
WT Room Temperature Brown fat, biological rep1 |
| GSM2696489 |
WT Room Temperature Brown fat, biological rep2 |
| GSM2696490 |
WT Room Temperature Brown fat, biological rep3 |
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| Relations |
| BioProject |
PRJNA393441 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE100924_RAW.tar |
50.3 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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