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| Status |
Public on Jul 23, 2018 |
| Title |
Identification of differentially expressed genes between control and miR-371~373 cluster-overexpressing colorectal cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The miR-371~373 cluster is a suspected repressor of colon cancer initiation and progression. To better understand its role in metastasis initiation, we used microarray expression analysis to identify potential target genes of this miRNA cluster
Potential target genes were defined as significantly downregulated genes after stable overexpression of the miR-371~373 cluster
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| Overall design |
We performed a stable overexpression of a control vector or a specific miR-371~373 cluster-containing vector in 2 different CRC spheroid cultures. Three technical replicates were used for each condition.
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| Citation(s) |
29748374 |
| Submission date |
Jul 28, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Elisabeth Letellier |
| E-mail(s) |
elisabeth.letellier@uni.lu
|
| Organization name |
University of Luxembourg
|
| Department |
Life Sciences Research Unit
|
| Lab |
Molecular Disease Mechanisms
|
| Street address |
6, Avenue du Swing
|
| City |
Belvaux |
| ZIP/Postal code |
L-4367 |
| Country |
Luxembourg |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA396177 |
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