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| Status |
Public on Aug 24, 2017 |
| Title |
Lenalidomide-mediated erythroid improvement in non-del(5q) myelodysplastic syndromes is associated with bone marrow immuno-remodeling [Affymetrix] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
In the field of MDS and on bone marrow mononuclear cells , we search for a signature which predict the response to Lenalidomide treatment.
This transcriptome study appended to the GFM-LEN-EPO-2008 clinical trial reports a predictive signature of response to lenalidomide and a unique immune response signature after treatment.
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| |
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| Overall design |
Examination of expression data before and after treatment by Len in non del(5q) MDS
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| |
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| Contributor(s) |
KOSMIDER O, KERDIVEL G, CHESNAIS V, BECHT E, DUMONT F, FONTENAY M, FRIDMAN H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 23, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Olivier KOSMIDER |
| E-mail(s) |
olivier.kosmider@aphp.fr
|
| Phone |
+33660680151
|
| Organization name |
Institut Cochin
|
| Street address |
27 Rue du faubourg Saint Jacques
|
| City |
Paris |
| ZIP/Postal code |
75014 |
| Country |
France |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (74)
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| This SubSeries is part of SuperSeries: |
| GSE132837 |
A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome |
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| Relations |
| BioProject |
PRJNA430776 |
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