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Status |
Public on Mar 31, 2021 |
Title |
Expression data MCF-7 Breast cancer cells with Graphene Oxide and Graphene nitrite Treatments |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Breast cancer is one of the fatal diseases, Graphene has a property that can be used for Imaging and Therapy. Global gene expression changes leading to these changes were investigated presently in Breast cancer subtypes. The pathological staging of the cancers is compared to global gene expression profiles. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process.
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Overall design |
Graphene Oxide and Graphene Nitrite was treated with IC25 vvalue in MCF-7 Breast cancer cell lines respectively. RNA extraction extraction and hybridization on Affymetrix microarrays were performed to under stand tumour progression with an intent to identify candidate markers for Imaging and therapy.
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Contributor(s) |
Elchuri SV, Athyala PK, Chittipothi S, Narayanan D |
Citation(s) |
33869917 |
Submission date |
Oct 13, 2017 |
Last update date |
Jul 25, 2021 |
Contact name |
Sailaja V Elchuri |
E-mail(s) |
sailaja.elchuri@gmail.com
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Organization name |
Vision Research Foundation
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Department |
Nanobiotechnology
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Lab |
Nanotechnology
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Street address |
No18, College Road, Nungambakkam
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City |
Chennai |
State/province |
Tamil Nadu |
ZIP/Postal code |
600006 |
Country |
India |
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Platforms (1) |
GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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Samples (7)
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Relations |
BioProject |
PRJNA414192 |