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| Status |
Public on Oct 20, 2017 |
| Title |
Transcriptome analysis of naive and Listeria monocytogenes-specific CD8+ T cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The histone methyltransferase Suv39h1 silences transcriptional programs during CD8+-T cell differentiation
The study explores the role of gene silencing by Suv39h1, a histone methyltransferase, that plays a critical role in heterochromatin dynamics.
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| |
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| Overall design |
Naïve littermate and Suv39h1-KO CD8+ T cells, and day 7 p.i. Kb-OVA+ CD8+ T cells (from Listeria m.-OVA infected mice), were isolated by FACS. RNA was isolated and analyzed using Affymetrix microarrays. microarrays (three mice per condition were analyzed).
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| |
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| Contributor(s) |
Pace L, Goudot C, Gentien D, Rapinat A |
| Citation(s) |
29326266 |
| Submission date |
Oct 19, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Luigia Pace |
| E-mail(s) |
Luigia.Pace@curie.fr
|
| Organization name |
Institut Curie
|
| Street address |
26 rue d'Ulm
|
| City |
Paris |
| ZIP/Postal code |
75005 |
| Country |
France |
| |
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| Platforms (1) |
| GPL17400 |
[MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA414985 |
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