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| Status |
Public on Dec 20, 2017 |
| Title |
Expression data from Huh7.5 hepatoma cells transfected with 100 nM miR-7 mimic |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Our work demonstrated that PPAR-α regulates miR-7, a microRNA which regulates SREBP1 signaling.
We used microarrays to detail the effect of miR-7 on hepatic gene expression, and, within activated genes, identified an enrichment for genes with SREBP1 binding sites in their promoters.
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| Overall design |
Huh7.5 cells were transfected with miR-7 or control mimics (100 nM), and total RNA was isolated 72 hours post-transfection.
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| Contributor(s) |
Singaravelu R, Pezacki JP |
| Citation(s) |
29321595 |
| Submission date |
Dec 19, 2017 |
| Last update date |
Jun 12, 2019 |
| Contact name |
John Paul Pezacki |
| E-mail(s) |
john.pezacki@uottawa.ca
|
| Organization name |
University of Ottawa
|
| Department |
Chemistry and Biomolecular Sciences
|
| Street address |
150 Louis-Pasteur Pvt
|
| City |
Ottawa |
| State/province |
ON |
| ZIP/Postal code |
K1N 6N5 |
| Country |
Canada |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA423013 |
