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Series GSE109029 Query DataSets for GSE109029
Status Public on Jan 10, 2019
Title Expression data from T24 cells after TRIP13 knockdown
Organism Homo sapiens
Experiment type Expression profiling by array
Summary TRIP13 is a crucial regulator of double-stranded break repair and spindle apparatus checkpoint and its abnormal expression has been found in several human cancers, whereas the role of TRIP13 in the malignant development of urothelial bladder cancer has not been fully elucidated.
We used microarrays to find out differrential expressed genes upon TRIP13 konckdown in T24 cells
 
Overall design T24 cells tranduced with lentiviruses expressing shTRIP13 or control vector were selected for RNA extraction and hybridization on Affymetrix microarrays.
 
Contributor(s) Gao Y, Guo Q
Citation(s) 31337978
Yanjun Gao, Shanhui Liu, Qi Guo, Su Zhang, Youli Zhao, Hanzhang Wang, Tianbao Li, Yuwen Gong, Yuhan Wang, Tao Zhang, Zhilong Dong, Dean Bacich, Wasim H. Chowdhury, Ronald Rodriguez, and Zhiping Wang. Increased expression of TRIP13 drives the tumorigenesis of bladder cancer in association with the EGFR signaling pathway. International Journal of Biological Sciences 2019. doi:10.7150/ijbs.32718
Submission date Jan 10, 2018
Last update date Jul 29, 2019
Contact name YANJUN GAO
E-mail(s) gyj305268145@126.com
Phone 13619397726
Organization name the 2nd Hospital of Lanzhou University
Department Urology
Street address 222 Tianshui South Road
City Lanzhou
State/province Gansu
ZIP/Postal code 730000
Country China
 
Platforms (1)
GPL15207 [PrimeView] Affymetrix Human Gene Expression Array
Samples (6)
GSM2928289 T24_KD_biological rep1
GSM2928290 T24_KD_biological rep2
GSM2928291 T24_KD_biological rep3
Relations
BioProject PRJNA429447

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE109029_Normalized_data_with_analysis.xlsx 18.6 Mb (ftp)(http) XLSX
GSE109029_RAW.tar 11.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record

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