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| Status |
Public on May 28, 2018 |
| Title |
The cAMP inducible Coactivator CRTC3 Attenuates Brown Adipose Tissue Thermogenesis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
CRTC3 deficiency in brown fat regulates brown fat function
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| Overall design |
4 day differentiated primary mouse SVF cells from Brown fat of wild-type or CRTC3 BKO mice treated or not with Forskolin (FSK), which activates the hormone adenylate cyclase. This compound is added to cell culture media to activate the PKA pathway.
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| Contributor(s) |
Yoon Y, Tsai W, Vandevelde S, Chen Z, Lee KF, Morgan DA, Rhamouni K, Matsumura S, Wiater E, Song Y, Montminy M |
| Citation(s) |
29784793, 34686752 |
| Submission date |
Jan 19, 2018 |
| Last update date |
Oct 27, 2021 |
| Contact name |
Ezra Wiater |
| E-mail(s) |
wiater@salk.edu
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| Phone |
(858)453-4100
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| Organization name |
Salk Institute For Biological Studies
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| Department |
PBL
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| Lab |
Montminy
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| Street address |
10010 N Torrey Pines Rd
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| City |
San Diego |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA430891 |
| SRA |
SRP131058 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE109443_CRTC3-Bko-SVF_gene_exp.diff.gz |
4.1 Mb |
(ftp)(http) |
DIFF |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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