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| Status |
Public on Nov 21, 2018 |
| Title |
Whole genome copy number profiles of FFPE samples from patients with metasatic colorectal cancer (mCRC) |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
Metastatic colorectal cancer (mCRC) is associated with multiple somatic copy number alterations (SCNAs). We analyzed SCNAs to estimate overall survival (OS) and progression free suvival (PFS) for mCRC patients treated with bevacizumab in combination with oxaliplatin or irinotecan.
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| |
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| Overall design |
Genomic DNAs were purified from 154 FFPE samples for mCRC patients treated with bevacizumab plus irinotecan (FOLFIRI) or oxaliplatin (FOLFOX) and the response was analyzed by array CGH profiling.
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| |
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| Contributor(s) |
Fujita Y, Nishio K |
| Citation(s) |
30425180 |
| Submission date |
Feb 19, 2018 |
| Last update date |
Feb 18, 2020 |
| Contact name |
Yoshihiko Fujita |
| E-mail(s) |
fujita@med.kindai.ac.jp
|
| Organization name |
Kinki university School of Medicine
|
| Street address |
377-2 Ohno-Higashi
|
| City |
Osaka-Sayama |
| ZIP/Postal code |
589-8511 |
| Country |
Japan |
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| Platforms (1) |
| GPL10123 |
Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version) |
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| Samples (154)
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| Relations |
| BioProject |
PRJNA434557 |
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