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| Status |
Public on Jun 13, 2019 |
| Title |
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [TCR-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
High numbers of tissue-resident memory T (TRM) cells have been associated with better clinical outcomes in cancer patients. However, the molecular characteristics that drive their efficient immune response to tumors are poorly understood. Here, using single-cell and bulk transcriptomic analysis of purified populations of TRM and non-TRM cells we characterise these populations
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| |
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| Overall design |
Population and single cell profiling of subtypes of CD8 cells isolated from human lung and lung tumour samples with flow cytometry
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| Contributor(s) |
Clarke J, Panwar B, Madrigal A, Singh D, Wood O, Chee S, Awad A, King E, Woo E, Alzetani A, Seumois G, Thomas G, Ganesan A, Friedmann P, Sanchez-Elsner T, Ay F, Ottensmeier C, Vijayanand P |
| Citation(s) |
31227543, 36701231 |
| Submission date |
Mar 15, 2018 |
| Last update date |
Aug 08, 2023 |
| Contact name |
Pandurangan Vijayanand |
| E-mail(s) |
vijay@lji.org
|
| Organization name |
La Jolla Institute for Allergy and Immunology
|
| Department |
Division of Vaccine Discovery
|
| Lab |
VD-Vijay
|
| Street address |
9420 Athena Circle
|
| City |
La Jolla |
| State/province |
California |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (20)
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| GSM3044527 |
Clarke_TCRseq_Beta_Donor-6_Tumor_CD8+_CD103pos |
| GSM3044528 |
Clarke_TCRseq_Beta_Donor-6_Tumor_CD8+_CD103neg |
| GSM3044529 |
Clarke_TCRseq_Beta_Donor-21_Tumor_CD8+_CD103pos |
| GSM3044530 |
Clarke_TCRseq_Beta_Donor-21_Tumor_CD8+_CD103neg |
| GSM3044531 |
Clarke_TCRseq_Beta_Donor-26_Tumor_CD8+_CD103pos |
| GSM3044532 |
Clarke_TCRseq_Beta_Donor-26_Tumor_CD8+_CD103neg |
| GSM3044533 |
Clarke_TCRseq_Beta_Donor-20_Tumor_CD8+_CD103pos |
| GSM3044534 |
Clarke_TCRseq_Beta_Donor-20_Tumor_CD8+_CD103neg |
| GSM3044535 |
Clarke_TCRseq_Beta_Donor-24_Tumor_CD8+_CD103pos |
| GSM3044536 |
Clarke_TCRseq_Beta_Donor-24_Tumor_CD8+_CD103neg |
| GSM3044537 |
Clarke_TCRseq_Beta_Donor-3_Tumor_CD8+_CD103pos |
| GSM3044538 |
Clarke_TCRseq_Beta_Donor-3_Tumor_CD8+_CD103neg |
| GSM3044539 |
Clarke_TCRseq_Beta_Donor-5_Tumor_CD8+_CD103pos |
| GSM3044540 |
Clarke_TCRseq_Beta_Donor-5_Tumor_CD8+_CD103neg |
| GSM3044541 |
Clarke_TCRseq_Beta_Donor-7_Tumor_CD8+_CD103pos |
| GSM3044542 |
Clarke_TCRseq_Beta_Donor-7_Tumor_CD8+_CD103neg |
| GSM3044543 |
Clarke_TCRseq_Beta_Donor-1_Tumor_CD8+_CD103pos |
| GSM3044544 |
Clarke_TCRseq_Beta_Donor-1_Tumor_CD8+_CD103neg |
| GSM3044545 |
Clarke_TCRseq_Beta_Donor-8_Tumor_CD8+_CD103pos |
| GSM3044546 |
Clarke_TCRseq_Beta_Donor-8_Tumor_CD8+_CD103neg |
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| This SubSeries is part of SuperSeries: |
| GSE111898 |
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer. |
|
| Relations |
| BioProject |
PRJNA438509 |
| SRA |
SRP135796 |
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