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| Status |
Public on May 31, 2018 |
| Title |
Differences in molecular expression in cases of non-viable ectopic and intrauterine pregnancies |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Ectopic pregnancy is the leading cause of morbidity and mortality among women in the first trimester. A reliable diagnostic test for the detection of ectopic pregnancy in cases of non-viable pregnancy of unknown location (NV-PUL) is needed. The objective of the current study is to define differences in molecular expression profiles in ectopic and abnormal intrauterine pregnancies toward discovery of biologically plausible ectopic classifier candidate. These samples come from a prospective cohort study comparing transcriptome profiles from women with ectopic pregnancy (ECT) or non-viable intrauterine pregnancy (NV-IUP). Samples were analyzed with the Affymetrix Human Gene 2.0 ST Array.
The views expressed are those of the author(s) and do not reflect the official policy of the Department of the Army, the Department of Defense or the U.S. Government.
The investigators have adhered to the policies for protection of human subjects as prescribed in 45 CFR 46.
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| Overall design |
17 endometrial biopsies taken from women with non-viable intrauterine (n=9) and ectopic (n=8) pregnancies
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| |
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| Contributor(s) |
Lentscher J, Ortogero N, Gillette L, Burney RO, Chow G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 09, 2018 |
| Last update date |
Mar 15, 2019 |
| Contact name |
Nicole Ortogero |
| Organization name |
University of Nevada, Reno
|
| Department |
Physiology and Cell Biology
|
| Lab |
Dr. Wei Yan
|
| Street address |
1664 N. Virginia St
|
| City |
Reno |
| State/province |
Nevada |
| ZIP/Postal code |
89557 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (17)
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| Relations |
| BioProject |
PRJNA449372 |
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