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Series GSE113623 Query DataSets for GSE113623
Status Public on Apr 26, 2018
Title Gene expression profile of tumor antigen-specific CD4 T cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary Up to know CD4 T cell antitumor responses have been mostly studied in transplanted tumor models. However, although they are valuable tools, they are not suitable to study the long term interactions between tumors and the immune system
We used gene expression profiling to characterize the fate of naive tumor antigen-specific CD4 T cells in a genetically-induced lung adenocarcinoma expressing the MHC-II restricted DBY antigen as a model tumor antigen.
 
Overall design Naïve DBY-specific Marilyn CD4 T (Marilyn) were transferred into mice bearing early or advanced tumors. Total tumor antigen-specific Marilyn CD4 T cells were purified from the tumor-draining lymph node 7 days after transfer.
 
Contributor(s) Alonso R, Lantz O
Citation(s) 29844317
Submission date Apr 24, 2018
Last update date Jul 26, 2018
Contact name Olivier Lantz
E-mail(s) olivier.lantz@curie.fr
Organization name Curie Institute
Lab U932
Street address 26 rue d'Ulm
City Paris
ZIP/Postal code 75005
Country France
 
Platforms (1)
GPL17400 [MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version]
Samples (15)
GSM3110405 Marilyn cells from mice bearing advanced tumors_biological rep_1
GSM3110406 Marilyn cells from mice bearing advanced tumors_biological rep_2
GSM3110407 Marilyn cells from mice bearing advanced tumors_biological rep_3
Relations
BioProject PRJNA453409

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE113623_RAW.tar 61.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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