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| Status |
Public on Apr 30, 2021 |
| Title |
Effect of Disease and Exercise in Skeletal Muscle of Patients with Peripheral Artery Disease |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
PAD is associated with reduced uptake of glucose and insulin resistance in skeletal muscle. In this study, we look at the effect of exercise on gene expression in patients with PAD.
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| Overall design |
Two types of patients were recruited for this study: patients with peripheral arterial disease (PAD) and healthy patients without the disease. Healthy patients were measured only once. PAD patients were measured twice: once at baseline, then a second time after each patient was randomly administered one of two treatments, exercise or control. The age of healthy patients was also recorded, as greater than or less than 50 year of age.
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| Contributor(s) |
Parmer C, De Sousa-Coelho AL, Daher G, Burkart A, Dreyfuss J, Pan H, Prenner J, Milian J, Pande R, Patti ME, Creager MA |
| Citation(s) |
32853041 |
| Submission date |
Apr 30, 2018 |
| Last update date |
Aug 16, 2022 |
| Contact name |
Grace Daher |
| Organization name |
Joslin Diabetes Center
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| Street address |
1 Joslin Place
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| City |
Boston |
| ZIP/Postal code |
02215 |
| Country |
USA |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (52)
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| GSM3122196 |
Healthy,no treatment,Baseline Jos5608(XH07) |
| GSM3122197 |
Healthy,no treatment,Baseline Jos5611(XH19) |
| GSM3122198 |
PAD,exercise,Final Jos5613(XP01-V2) |
| GSM3122199 |
PAD,exercise,Baseline Jos5614(XP03-V1) |
| GSM3122200 |
PAD,exercise,Final Jos5615(XP03-V2) |
| GSM3122201 |
PAD,no exercise,Final Jos5617(XP07-V2) |
| GSM3122202 |
PAD,exercise,Baseline Jos5618(XP19-V1) |
| GSM3122203 |
PAD,exercise,Final Jos5619(XP19-V2) |
| GSM3122204 |
PAD,exercise,Baseline Jos5620(XP06-V1) |
| GSM3122205 |
PAD,exercise,Final Jos5621(XP06-V2) |
| GSM3122206 |
PAD,no exercise,Final Jos5623(XP11-V2) |
| GSM3122207 |
PAD,no exercise,Baseline Jos5624(XP12-V1) |
| GSM3122208 |
PAD,no exercise,Final Jos5625(XP12-V2) |
| GSM3122209 |
PAD,no exercise,Baseline Jos5626(XP18-V1) |
| GSM3122210 |
PAD,no exercise,Final Jos5627(XP18-V2) |
| GSM3122211 |
PAD,no exercise,Baseline Jos5628(XP23-V1) |
| GSM3122212 |
PAD,no exercise,Final Jos5629(XP23-V2) |
| GSM3122213 |
Healthy,no treatment,Baseline Jos5651(XH28) |
| GSM3122214 |
Healthy,no treatment,Baseline Jos5652(XH29) |
| GSM3122215 |
Healthy,no treatment,Baseline Jos5653(XH02) |
| GSM3122216 |
Healthy,no treatment,Baseline Jos5654(XH10) |
| GSM3122217 |
PAD,no treatment,Baseline Jos5655(XP10-V1) |
| GSM3122218 |
PAD,exercise,Baseline Jos5656(XP01-V1_2) |
| GSM3122219 |
PAD,no treatment,Baseline Jos5657(XP21-V1) |
| GSM3122220 |
Healthy,no treatment,Baseline Jos5658(XH14) |
| GSM3122221 |
PAD,no treatment,Baseline Jos5659(XP08-V1) |
| GSM3122222 |
Healthy,no treatment,Baseline Jos5660(XH23) |
| GSM3122223 |
PAD,no exercise,Baseline Jos5797(2) (XP04-V1) |
| GSM3122224 |
PAD,no exercise,Final Jos5798_b(3) (XP04-V2) |
| GSM3122225 |
PAD,no exercise,Baseline Jos5799(4) (XP27-V1) |
| GSM3122226 |
PAD,no exercise,Final Jos5800(5) (XP27-V2) |
| GSM3122227 |
PAD,no treatment,Baseline Jos5801(8) (XP20) |
| GSM3122228 |
PAD,no treatment,Baseline Jos5802(10) (XP14) |
| GSM3122229 |
PAD,no treatment,Baseline Jos5803(11) (XP17) |
| GSM3122230 |
PAD,no treatment,Baseline Jos5804(12) (XP24) |
| GSM3122231 |
PAD,no treatment,Baseline Jos5805(14) (XP26) |
| GSM3122232 |
Healthy,no treatment,Baseline Jos5809(18) (XH12) |
| GSM3122233 |
Healthy,no treatment,Baseline Jos5810(19) (XH13) |
| GSM3122234 |
PAD,no exercise,Baseline Jos5817(21) (XP07-V1) |
| GSM3122235 |
PAD,no exercise,Baseline Jos5818(22) (XP11-V1) |
| GSM3122236 |
PAD,no treatment,Baseline Jos5820(25) (XP31-V1) |
| GSM3122237 |
PAD,no treatment,Baseline Jos5821(26) (XP25-V1) |
| GSM3122238 |
PAD,no exercise ,Baseline Jos6113(3)(XP32-B) |
| GSM3122239 |
PAD,no exercise,Final Jos6114(4)(XP32-F) |
| GSM3122240 |
PAD,no exercise,Baseline Jos6115(5)(XP33-B) |
| GSM3122241 |
PAD,no exercise,Final Jos6116(6)(XP33-F) |
| GSM3122242 |
PAD,exercise,Final Jos6117(7)(XP35-F) |
| GSM3122243 |
PAD,no treatment,Baseline Jos6118(8)(XP38-B) |
| GSM3122244 |
PAD,exercise,Baseline Jos6119(9)(XP39-B) |
| GSM3122245 |
PAD,exercise,Final Jos6120(10)(XP39-F) |
| GSM3122246 |
PAD,exercise,Final Jos6122(4c)(XP34-F) |
| GSM3122247 |
PAD,no treatment,Baseline Jos5819(23) (XP29-V1) |
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| Relations |
| BioProject |
PRJNA454312 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE113873_RAW.tar |
95.8 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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