|
| Status |
Public on Dec 25, 2018 |
| Title |
Type 1 interferon signaling is crucial from the loss of tolerance nd the development of autoreactive B cells. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The transcriptomes of FACS-sorted B220+GL7+CD95+ germinal center B cells and B220+GL7-CD95- non-germinal center B cells from lupus-prone B6.Sle1b were compared to the same cell types in B6.Sle1b mice without the type 1 interferon receptor (B6.Sle1b.IFNaR1-/-).
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| |
|
| Overall design |
Examination of effect of IFNaR1 signaling on B cell selection in autoimmune-prone germinal centers.
|
| |
|
| Contributor(s) |
Domeier P, Babu Chodisetti S, Schell SL, Imamura Kawasawa Y, Fasnacht MJ, Soni C, Rahman ZS |
| Citation(s) |
29996101 |
| Submission date |
Jun 05, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
Yuka Imamura Kawasawa |
| E-mail(s) |
yui102@psu.edu
|
| Organization name |
Penn State University
|
| Department |
College of Medicine, Pharmacology
|
| Street address |
500 University Dr.
|
| City |
Hershey |
| State/province |
PA |
| ZIP/Postal code |
17033 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA474672 |
| SRA |
SRP149792 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE115349_PD09_v_PD11.batch1.novel.gene_exp.diff.txt.gz |
7.9 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD09_v_PD12.batch1.novel.gene_exp.diff.txt.gz |
8.3 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD10_v_PD11.batch1.novel.gene_exp.diff.txt.gz |
8.4 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD10_v_PD12.batch1.novel.gene_exp.diff.txt.gz |
8.9 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD11_v_PD12.batch1.novel.gene_exp.diff.txt.gz |
8.5 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD19_v_PD20.batch2.novel.gene_exp.diff.txt.gz |
8.0 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD19_v_PD21.batch2.novel.gene_exp.diff.txt.gz |
8.1 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD19_v_PD22.batch2.novel.gene_exp.diff.txt.gz |
8.1 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD20_v_PD21.batch2.novel.gene_exp.diff.txt.gz |
8.1 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD20_v_PD22.batch2.novel.gene_exp.diff.txt.gz |
8.2 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD21_v_PD22.batch2.novel.gene_exp.diff.txt.gz |
8.3 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD28_v_PD29.batch3.novel.gene_exp.diff.txt.gz |
11.2 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD28_v_PD30.batch3.novel.gene_exp.diff.txt.gz |
11.5 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD28_v_PD31.batch3.novel.gene_exp.diff.txt.gz |
10.7 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD29_v_PD30.batch3.novel.gene_exp.diff.txt.gz |
10.8 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD29_v_PD31.batch3.novel.gene_exp.diff.txt.gz |
10.2 Mb |
(ftp)(http) |
TXT |
| GSE115349_PD30_v_PD31.batch3.novel.gene_exp.diff.txt.gz |
10.3 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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