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| Status |
Public on Mar 08, 2019 |
| Title |
Genome-wide maps of ΔNLef1 in primary mouse keratinocytes |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
In adult K14ΔNLef1 mouse, the overexpression of ∆NLef1, a ß-catenin dominat negative, in basal keratinocytes leads to the conversion of hair follicles into multilayered epithelial cysts and ectopic sebaceous gland. To uncover direct target genes of ΔNLef1 we performed ChIP-Seq experiments.
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| |
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| Overall design |
Examination of ∆NLef1 genomic targets in mouse primary keratinocytes
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| |
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| Contributor(s) |
Donati G, Watt F |
| Citation(s) |
30886049 |
| Submission date |
Aug 03, 2018 |
| Last update date |
May 09, 2019 |
| Contact name |
Giacomo Donati |
| E-mail(s) |
giacomo.donati@kcl.ac.uk
|
| Organization name |
King's College London
|
| Street address |
Guy's Hospital, Great Maze Pond
|
| City |
London |
| ZIP/Postal code |
SE1 9RT |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
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| Samples (3) |
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| This SubSeries is part of SuperSeries: |
| GSE62608 |
Gata6 network regulates epidermal junctional zone cell fate. |
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| Relations |
| BioProject |
PRJNA484337 |
| SRA |
SRP156267 |
