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| Status |
Public on Oct 10, 2018 |
| Title |
Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution |
| Organism |
Canis lupus familiaris |
| Experiment type |
Genome variation profiling by SNP array
SNP genotyping by SNP array
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| Summary |
Through thousands of years of breeding and strong human selection, the dog (Canis lupus familiaris) exists today within hundreds of closed populations throughout the world, each with defined phenotypes. A singular geographic region with broad diversity in dog breeds presents an interesting opportunity to observe potential mechanisms of breed formation. Italy claims 14 internationally recognized dog breeds, with numerous additional local varieties. To determine the relationship among Italian dog populations, we integrated genetic data from 263 dogs representing 23 closed dog populations from Italy, seven Apennine gray wolves. Using 142,840 genome-wide SNPs, this dataset was used in the identification of breed development routes for the Italian breeds that included divergence from common populations for a specific purpose, admixture of regional stock with that from other regions, and isolated selection of local stock with specific attributes.
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| Overall design |
273 canid samples representing 21 Italian breeds and seven Apennine gray wolves
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| Contributor(s) |
Dreger DL, Talenti A, Frattini S, Polli M, Marelli S, Harris AC, Liotta L, Cocco R, Hogan AN, Bigi D, Caniglia R, Parker HG, Pagnacco G, Ostrander EA, Crepaldi P |
| Citation(s) |
29531705, 36669004, 36899675 |
| Submission date |
Oct 09, 2018 |
| Last update date |
Jun 23, 2023 |
| Contact name |
Alexander Christian Harris |
| E-mail(s) |
alex.harris@nih.gov
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| Phone |
301-402-2016
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| Organization name |
National Institutes of Health
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| Department |
National Human Genome Research Institute
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| Lab |
Ostrander
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| Street address |
50 South Drive
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| City |
Bethesda |
| State/province |
Maryland |
| ZIP/Postal code |
20892 |
| Country |
USA |
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| Platforms (1) |
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| Samples (273)
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| Relations |
| BioProject |
PRJNA495376 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE121027_GEO_Dreger_100418_DetailedGenotypesCalls.txt.gz |
51.1 Mb |
(ftp)(http) |
TXT |
| GSE121027_GEO_Dreger_100418_GenotypeCalls.txt.gz |
26.6 Mb |
(ftp)(http) |
TXT |
| GSE121027_GEO_Dreger_100418_Intensities1.txt.gz |
429.6 Mb |
(ftp)(http) |
TXT |
| GSE121027_GEO_Dreger_100418_MatrixProcessed1.txt.gz |
535.0 Mb |
(ftp)(http) |
TXT |
| GSE121027_RAW.tar |
720.1 Mb |
(http)(custom) |
TAR (of IDAT) |
| Processed data are available on Series record |
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