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Series GSE122061 Query DataSets for GSE122061
Status Public on Jul 27, 2020
Title Dissecting the Genetic Architecture of Renal Function and the biomarker Cystatin C in Aging
Organism Mus musculus
Experiment type Expression profiling by array
Summary In this study, we utilized 95 Diversity Outbred (DO) female mice, 56 weeks of age, to perform eQTL analysis of renal biomarkers in blood and urine. We also determined the correlation between kidney biomarkers and expression levels of the genes in kidney.
 
Overall design Female Diversity Outbred mice (n = 120; J: DO; G16; JAX stock number 009376) were obtained from the Jackson Laboratory (Bar Harbor, ME) at 4 weeks of age. The mice were group housed (n = 5 mice per cage) and maintained on chow diets. At about 56 weeks of age, mice were injected intraperitoneally with a volume of sterile isotonic saline equivalent to 10 percent of their body weight and on the following day mice were fasted for 4 hours, anesthetized, and dissected to kidney samples for micro array analysis. Microarray data were available from 95 kidney samples
 
Contributor(s) Bennett BJ, Huda MN
Citation(s) 32467129
Submission date Nov 01, 2018
Last update date Jul 27, 2020
Contact name Brian J Bennett
E-mail(s) brian.bennett@ars.usda.gov
Organization name Western Human Nutrition Research Center, ARS
Department Obesity and Metabolism
Street address 430 West Health Sciences Drive
City Davis
State/province CA
ZIP/Postal code 95616
Country USA
 
Platforms (1)
GPL17400 [MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version]
Samples (95)
GSM3453950 Kidney_Elderly_DO_Female_Mice_G16_ID_003
GSM3453951 Kidney_Elderly_DO_Female_Mice_G16_ID_006
GSM3453952 Kidney_Elderly_DO_Female_Mice_G16_ID_007
Relations
BioProject PRJNA503348

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Supplementary file Size Download File type/resource
GSE122061_RAW.tar 430.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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