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| Status |
Public on Apr 17, 2019 |
| Title |
Next generation sequencing analysis of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Cisplatin-resistant gastric cancer (GC) occurs in patients with GC treated with cisplatin-based chemotherapy, which results in disease progression and early recurrence during the treatment. To understand the initiation and developmental mechanism underlying cisplatin-resistant GC, we developed cisplatin resistant SGC7901 cells (SGC7901/DDP) from the parental cells (SGC7901/S) by continuous exposure to increasing concentrations of cisplatin and subjected these two cell lines to RNA sequencing analysis.
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| Overall design |
mRNA profiles of cisplatin resistant SGC7901 cells (SGC7901/DDP) and the parental cells (SGC7901/S) were generated by deep sequencing, using BGISEQ-500.
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| Contributor(s) |
Ou H, Yang D |
| Citation(s) |
30938333 |
| Submission date |
Nov 05, 2018 |
| Last update date |
Apr 17, 2019 |
| Contact name |
Libo Li |
| Organization name |
Dongguan People's Hospital
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| Department |
Department of General Surgery
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| Street address |
No.3 Wan Road, Dongguan, Guangdong
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| City |
Dongguan |
| ZIP/Postal code |
523000 |
| Country |
China |
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| Platforms (1) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA503804 |
| SRA |
SRP167825 |
