|
| Status |
Public on Mar 06, 2019 |
| Title |
Next generation sequening on control salivary submandibular glands versus glands from mice with an epithelial deletion in SOX10 via the Cre-Flox system |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report sequencing data on fetal mouse submandibular glands (SMGs) where SOX10 was deleted in the epithelia. By obtaining embryonic day 16 (E16) SMGs, we compared control glands with glands where SOX10 was deleted in the epithelial compartment. We found that loss of SOX10 resulted in smaller glands, which had reduced expression of genes related to the initiation of acinar, myoepithelial and intercalated duct cells.
|
| |
|
| Overall design |
Examination of gene expression in 2 different glands.
|
| |
|
| Contributor(s) |
Lombaert I |
| Citation(s) |
30713042 |
| Submission date |
Dec 04, 2018 |
| Last update date |
Mar 06, 2019 |
| Contact name |
Isabelle Lombaert |
| Organization name |
University of Michigan
|
| Street address |
2800 Plymouth Rd
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL15103 |
Illumina HiSeq 1000 (Mus musculus) |
|
| Samples (7)
|
|
| Relations |
| BioProject |
PRJNA508384 |
| SRA |
SRP172844 |
Less...
More...