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| Status |
Public on May 24, 2019 |
| Title |
Expression of IDO1-2, iNOS and interferon-inducible GTPases in Chlamydia muridarum infected BALB/c mouse lung tissues |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We wanted to screen the expression of known and putative antichlamydial genes in vivo. As an open approach, we performed RNA sequencing of Chlamydia muriadrum infected mouse lung tissues. RNA seq revealed that a diverse set of antichlamydial genes were induced by the infection, including previously described unique human and murine genes. We further characterized the source and activity of indolamine 2,3-dioxygenase genes, previously described as key human effectors.
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| |
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| Overall design |
Comparison of Chlamydia muridarum infected and uninfected BALB/c mouse lung tissues
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| |
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| Contributor(s) |
Virok DP, Burián K |
| Citation(s) |
31249813 |
| Submission date |
Dec 18, 2018 |
| Last update date |
Sep 03, 2019 |
| Contact name |
Dezső Peter Virok |
| E-mail(s) |
virok.dezso.peter@med.u-szeged.hu
|
| Organization name |
University of Szeged
|
| Department |
Department of Medical Microbiology and Immunobiology
|
| Street address |
Dóm tér 10.
|
| City |
Szeged |
| State/province |
Please select |
| ZIP/Postal code |
6720 |
| Country |
Hungary |
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| Platforms (1) |
| GPL16173 |
Illumina HiScanSQ (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA510547 |
| SRA |
SRP173776 |
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