|
| Status |
Public on Jan 04, 2019 |
| Title |
RNA sequencing results of L1-FGGY+/- lung squamous cell carcinoma tumor samples |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In order to explore pathways which were affected by L1-FGGY in lung squamous cell carcinoma (LUSC), we performed RNA sequencing on L1-FGGY+/- LUSC tumor samples. We identified 1529 (826 up and 703 down) dysregulated genes in L1-FGGY positive tissues with an adjusted p value less than 0.05. The KEGG enrichment analysis indicated that many signaling pathways were upregulated in L1-FGGY positive tissues, including glutathione metabolism, metabolism of xenobiotics by cytochrome P450, arachidonic acid metabolism, metabolic pathways, and glycerolipid metabolism, most of which were metabolic pathways, especially in lipid-related metabolism.
|
| |
|
| Overall design |
RNA sequencing profiles of L1-FGGY+/- LUSC tumor samples were generated by deep sequencing, in triplicate, using Illumina NovaSeq, followed by differential expression analysis and KEGG enrichment analysis.
|
| |
|
| Contributor(s) |
Zhang R, Sun Z |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 03, 2019 |
| Last update date |
Apr 20, 2022 |
| Contact name |
Zeguo Sun |
| E-mail(s) |
zeguo.sun@mssm.edu
|
| Phone |
6466427380
|
| Organization name |
Ichan School of Medicine at Mount Sinai
|
| Street address |
1468 Madison Avenue
|
| City |
New York |
| ZIP/Postal code |
10029 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (19)
|
|
| Relations |
| BioProject |
PRJNA512867 |
| SRA |
SRP175171 |
Less...
More...