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| Status |
Public on Oct 24, 2019 |
| Title |
Single-cell RNA sequencing reveals regulatory mechanism for trophoblast cell-fate divergence in human peri-implantation embryo |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We studied the transcriptomic dynamics underlying human per-implantation development of trophoblast cells.
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| |
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| Overall design |
We obtained human peri-implantation embryos through blastocyst to early post -implantation stages using an in vitro coculture system, and profiled transcriptome of individual trophoblast cells collected from these embryos. By systematic analysis methods, we revealed the genetic networks regulating peri-implantation trophoblast development.
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| |
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| Contributor(s) |
An Q, Lv B |
| Citation |
Single-Cell RNA Sequencing Reveals Regulatory Mechanism for Trophoblast Cell-Fate Divergence in Human Peri-Implantation EmbryoBo Lv, Qin An, Qiao Zeng, Ping Lu, Xianmin Zhu, Yazhong Ji, Guoping Fan, Zhigang Xue; bioRxiv 567362; doi: https://doi.org/10.1101/567362
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| Submission date |
Jan 24, 2019 |
| Last update date |
Oct 24, 2019 |
| Contact name |
Qin An |
| E-mail(s) |
anqin314@gmail.com
|
| Organization name |
ucla
|
| Department |
Department of Human Genetics
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| Lab |
Guoping Fan Lab
|
| Street address |
Room 6554 Gonda Building, UCLA
|
| City |
los angeles |
| State/province |
CALIFORNIA |
| ZIP/Postal code |
90024 |
| Country |
USA |
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| Platforms (1) |
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| Samples (640)
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| Relations |
| BioProject |
PRJNA516921 |
| SRA |
SRP181926 |
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