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Status |
Public on Jun 13, 2019 |
Title |
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ATAC-Seq] |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
High numbers of tissue-resident memory T (TRM) cells have been associated with better clinical outcomes in cancer patients. However, the molecular characteristics that drive their efficient immune response to tumors are poorly understood. Here, using single-cell and bulk transcriptomic analysis of purified populations of TRM and non-TRM cells we characterise these populations
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Overall design |
Population and single cell profiling of subtypes of CD8 cells isolated from human lung and lung tumour samples with flow cytometry
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Contributor(s) |
Clarke J, Panwar B, Madrigal A, Singh D, Wood O, Chee S, Awad A, King E, Woo E, Alzetani A, Seumois G, Thomas G, Ganesan A, Friedmann P, Sanchez-Elsner T, Ay F, Ottensmeier C, Vijayanand P |
Citation(s) |
31227543, 36701231 |
Submission date |
Jan 29, 2019 |
Last update date |
Aug 08, 2023 |
Contact name |
Pandurangan Vijayanand |
E-mail(s) |
vijay@lji.org
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Organization name |
La Jolla Institute for Allergy and Immunology
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Department |
Division of Vaccine Discovery
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Lab |
VD-Vijay
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Street address |
9420 Athena Circle
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City |
La Jolla |
State/province |
California |
ZIP/Postal code |
92037 |
Country |
USA |
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Platforms (2) |
GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (9)
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This SubSeries is part of SuperSeries: |
GSE111898 |
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer. |
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Relations |
BioProject |
PRJNA517712 |
SRA |
SRP182843 |