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| Status |
Public on Dec 08, 2020 |
| Title |
Genome-wide identification of AP-2α targets in bladder cells by RNA-seq (Control vs AP-2α KD) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
TFAP2A (AP-2α) is a member of the transcription factor AP-2 family, functions as a tumor suppressor by regulating the expression of various cancer-related genes; its expression is positively correlated with chemosensitivity and survival of cancer patients.
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| Overall design |
SV-HUC-1 cells were infected with a lentivirus expressing scramble shRNA or AP-2α shRNA for 48 h and then the cells were selected with puromycin (1 µg/mL). Cells infected with scramble shRNA (control) and AP-2α shRNA were sequenced by Illumina HiSeq2000.
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| Contributor(s) |
Zhou J, Zhou J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Mar 22, 2019 |
| Last update date |
Dec 09, 2020 |
| Contact name |
Jianlin Zhou |
| E-mail(s) |
jlzhou@hunnu.edu.cn
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| Phone |
+8613755191079
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| Organization name |
Hunan Normal University
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| Department |
College of Life Science
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| Street address |
36 lushan road
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| City |
Changsha |
| State/province |
Hunan |
| ZIP/Postal code |
410081 |
| Country |
China |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE128716 |
Genome-wide identification of AP-2α targets in bladder cells by RNA-seq |
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| Relations |
| BioProject |
PRJNA528627 |
| SRA |
SRP189159 |
