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| Status |
Public on Feb 29, 2020 |
| Title |
The effect of oncogenic KrasG12D on the expression of inflammation-related genes in myeloid cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Oncogenic Ras mutations occur frequently in hematological malignancies. It was unclear if besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the development of the disease. We used microarray-based analysis of murine hematopoietic bone marrow (BM) cells harboring active inducible KrasG12D to reveal the expression of inflammation-related genes.
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| Overall design |
8 samples each of them from an individual mouse (biological replicate) were analyzed
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| Contributor(s) |
Hamarsheh S, Zeiser R, Andrieux G, Boerries M |
| Citation(s) |
32246016 |
| Submission date |
May 29, 2019 |
| Last update date |
Jun 02, 2020 |
| Contact name |
Geoffroy Andrieux |
| Organization name |
University clinics Freiburg
|
| Street address |
Breisacherstr 153
|
| City |
Freiburg |
| ZIP/Postal code |
79110 |
| Country |
Germany |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA545239 |
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