|
| Status |
Public on May 03, 2021 |
| Title |
Intratumoral TFR cells curtail anti-PD-1 treatment efficacy [human] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Follicular regulatory T cells (TFR cells) and their functional role in cancer have been completely disregarded so far. Our data identify that as a critical oversight, as these cells account for a substantial proportion of tumor-infiltrating CD4+ T cells
|
| |
|
| Overall design |
Assessment of the transcriptomic profile of tumor-infiltrating TREG and TFR cells
|
| Web link |
https://doi.org/10.2139/ssrn.3596586
|
| |
|
| Contributor(s) |
Eschweiler S, Clarke J, Ramirez Suastegui C, Panwar B, Madrigal A, Chee SJ, Woo E, Alzetani A, Friedmann P, Sanchez-Elsner T, Ay F, Ottensmeier C, Vijayanand P |
| Citation(s) |
34168370 |
| Submission date |
Jun 06, 2019 |
| Last update date |
Aug 02, 2021 |
| Contact name |
Pandurangan Vijayanand |
| E-mail(s) |
vijay@lji.org
|
| Organization name |
La Jolla Institute for Allergy and Immunology
|
| Department |
Division of Vaccine Discovery
|
| Lab |
VD-Vijay
|
| Street address |
9420 Athena Circle
|
| City |
La Jolla |
| State/province |
California |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (20)
|
|
| This SubSeries is part of SuperSeries: |
| GSE132297 |
Intratumoral TFR cells curtail anti-PD-1 treatment efficacy |
|
| Relations |
| BioProject |
PRJNA547554 |
| SRA |
SRP200649 |
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