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Series GSE133008 Query DataSets for GSE133008
Status Public on Feb 03, 2020
Title RNA-seq analysis after IRF4 and p65 knockdown in TL-Om1 cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-seq analysis was performed in an adult T-cell leukemia/lymphoma cell line (TL-Om1) to analyze gene expression changes after IRF4 or p65 knockdown.
 
Overall design Lentiviral shRNA transduction was carried out in TL-Om1 cells to knock down control (GFP), IRF4 or p65 gene. Two different shRNAs were used to target each gene in biological duplicates. Total RNA was harvested 3 days after knockdown and RNA-seq analysis was performed.
 
Contributor(s) Wong R, Tan TK, Sanda T
Citation(s) 31972002
Submission date Jun 19, 2019
Last update date May 04, 2020
Contact name Tze King Tan
Organization name National University of Singapore
Department Cancer Science Institute
Lab Takaomi Sanda Lab
Street address 14 Medical Drive
City Singapore
ZIP/Postal code 117599
Country Singapore
 
Platforms (1)
GPL23227 BGISEQ-500 (Homo sapiens)
Samples (12)
GSM3898186 GFP_sh1_dup1
GSM3898187 GFP_sh1_dup2
GSM3898188 GFP_sh2_dup1
This SubSeries is part of SuperSeries:
GSE133042 Oncogenic Regulatory Network Driven by IRF4 and NF-kappaB in Adult T-cell Leukemia/Lymphoma
Relations
BioProject PRJNA549684
SRA SRP201887

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE133008_DEG_IRF4_KD.txt.gz 2.0 Mb (ftp)(http) TXT
GSE133008_DEG_p65_KD.txt.gz 2.0 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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