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| Status |
Public on Apr 27, 2020 |
| Title |
Developmental trajectory of pre-hematopoietic stem cell formation from endothelium (scATAC-seq data set) |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To examine the cell and molecular transitions between endothelial (E), hemogenic endothelial (HE), and intra-arterial clusters (IAC) cells, we profiled ~1700 cells from the caudal arteries (dorsal aorta, umbilical, vitelline) of embryonic day (E) 10.5 mouse embryos by single-cell ATAC sequencing (scATAC-Seq). We found extensive cis--regulatory landscape change during the endothelial to hematopoietic transition (EHT).
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| Overall design |
Single cell ATAC-seq profiles of cells involved in endothelial to hematopoietic transition (EHT) from mouse embryos at embryonic day 10.5
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| Contributor(s) |
Tan K, Speck NA |
| Citation(s) |
32392346 |
| Submission date |
Sep 09, 2019 |
| Last update date |
Apr 10, 2023 |
| Contact name |
Qin Zhu |
| Organization name |
UCSF
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| Street address |
600 Minnesota Street
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| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94107 |
| Country |
USA |
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| Platforms (1) |
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| Samples (1) |
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| This SubSeries is part of SuperSeries: |
| GSE137117 |
Developmental trajectory of pre-hematopoietic stem cell formation from endothelium |
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| Relations |
| BioProject |
PRJNA564577 |
| SRA |
SRP221063 |
