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| Status |
Public on Nov 16, 2019 |
| Title |
CADM1-overexpression ES-2 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
CADM1, an immunoglobulin superfamily member, frequently inactivated but function as a tumor suppressor in many solid tumors. However, how CADM1 expression in ovarian cancer cells and the mechanisms of its tumor suppressor function is not fully understood.
We created ovarian cancer ES-2 cell lines in which CADM1 was stably up-regulated. Genes differentially expressed in CADM1-overexpressing ES-2 cells.
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| Overall design |
To uncover the upstream regulatory pathways of CADM1 as a tumor suppressor in ovarian cancer, we performed RNA microarray profiling on both CADM1-overexpressed group ES-2 cells and mock control group cells. Gene expression profiles were obtained by microarray analysis using Affymetrix GeneChip® PrimeView™ Human Gene Expression Array.
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| Contributor(s) |
Xu F, Si X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 15, 2019 |
| Last update date |
Nov 18, 2019 |
| Contact name |
Wang Hui |
| E-mail(s) |
wanghui01@caas.cn
|
| Phone |
+869312115262
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| Organization name |
Chinese Academy of Agricultural Scien
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| Street address |
QIlihe, Jiangouyan, NO.335
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| City |
Lanzhou |
| State/province |
Gansu |
| ZIP/Postal code |
730050 |
| Country |
China |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA589830 |
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